tert-butyl 2 4-dioxopiperidine-1-carboxylate (CAS# 845267-78-9)

Foromo ea limolek'hule	C10H15NO4
'Misa oa Molar	213.23
Botenya	1.199
Boling Point	373.8±35.0 °C(E boletsoeng esale pele)
Flash point	179.9°C
Khatello ea Mouoane	8.72E-06mmHg ho 25°C
pKa	10.67±0.20(E boletsoeng esale pele)
Boemo ba polokelo	Boloka sebakeng se lefifi, se tiisitsoe moo ho omileng, Mocheso oa Kamore
Refractive Index	1.493
MDL	MFCD10566071

Lintlha tsa Sehlahisoa

Likhoutu tsa Kotsi	20/21/22 - E kotsi ka ho hema, ho kopana le letlalo le haeba e koetsoe.
Tlhaloso ea Tšireletseho	S23 - Se ke oa hema mouoane. S24/25 - Qoba ho kopana le letlalo le mahlo.
WGK Jeremane	3
Khoutu ea HS	29337900

Sebelisa	2, 4-dipiperidon-1-formate tert-butyl formate ke motsoako oa phenoxymethyl-dihydrothiazolopyridone derivatives Reactants sehlahisoa, e le modulator e khethiloeng e ntle ea sebopeho (PAM) ea metabolized glutamate 5 (mGlu5) receptor.
kopo	2, 4-dioperidone-1-tert-butyl formate e sebelisoa haholo-holo e le organic intermediate le pharmaceutical intermediate, 'me e ka sebelisoa ho etsa lipatlisiso tsa laboratori le ts'ebetso ea nts'etsopele le ts'ebetso ea motsoako oa meriana ea lik'hemik'hale.
tokisetso	mohato a: eketsa EDCI (191.7g) ho DMF (400mL) tharollo ea 3-(tert-butoxycarbonylamino) propionic acid (189.2g,1.0mol), meldamic acid (144.1g,1.0mol) le DMAP (135.0g,1.1mol) ) e pholile ka ho hlatsoa leqhoa, 1.0mol). Li-reactants tse hlahisitsoeng li ile tsa tsosoa bosiu bo le bong mocheso oa kamore. Karabelo e ile ea tima ka 200mL H2O. The sephetho motsoako ile a phaella ka dropwise ho H2O (2.0L) tlas'a mechine susumetsang maikutlo. Se tiileng se fumanoeng se ile sa tlhotloa 'me sa hlatsuoa hantle ka metsi ho pH 7 ho fumana sehlahisoa (283g,90% chai). Mohato oa B: Tharollo ea 3-(2, 2-dimethyl-4, 6-dioxo-1, 3-dioxan-5-yl)-3-oxopropylcarbamate tert-butyl ester (100g,317.46mmol) ka toluene (1500mL) e futhumatsoa ka 100 ° C ka lihora tse 4. Li-reactants li pholile ka mocheso oa kamore 'me li tsepamisitsoe tlas'a khatello e fokolang ho fumana sehlahisoa se tala. Sehlahisoa (56g, 83% lihlahisoa) se hloekisitsoe ke MTBE-sila.