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Litaba

Tlhahlobo ea 'maraka: 3,5-di-tert-butyl-4-hydroxybenzyl alcohol (CAS 88-26-6) e le motsoako oa meriana le ho roala United States le Europe.

Indasteri ea meriana e ntse e tsoela pele ho fetoha 'me e beha khatello e ntseng e eketseha ho nts'etsopele ea mekhoa e tsoetseng pele ea phano ea meriana. E 'ngoe ea lintlha tse ka sehloohong tsa ho iphetola ha lintho ke tšebeliso ea li-additives tse khethehileng ho ntlafatsa ts'ebetso le botsitso ba metsoako ea lithethefatsi. Har'a bona, 3,5-di-tert-butyl-4-hydroxybenzyl joala (CAS88-26-6) e fetohile sebapali sa bohlokoa, haholo-holo tšimong ea li-additives tsa ho roala meriana.

 

Profile ea lik'hemik'hale le Thepa

 

3,5-di-tert-butyl-4-hydroxybenzyl joala ke motsoako oa phenolic o tsejoang ka thepa ea oona ea antioxidant. Sebopeho sa eona se ikhethang sa lik'hemik'hale se e lumella hore e sebetse ka katleho e le ho tsitsisa le ho boloka lintho tse sa tšoaneng. Motsoako ona o khetholloa ke bokhoni ba oona ba ho thibela ho senyeha ha oxidative, e leng habohlokoa ho boloka katleho le bophelo ba sethala sa lihlahisoa tsa meriana. Thepa ena e etsa hore e be ea bohlokoa ka ho khetheha mekhoeng ea ho roala e sireletsang metsoako e sebetsang ea meriana (APIs) ho tloha linthong tsa tikoloho tse kang mongobo le leseli.

 

Tšebeliso ea 'maraka oa meriana

 

Lefapheng la meriana, litlolo li phetha karolo ea bohlokoa tsamaisong ea phano ea lithethefatsi. Li sebelisetsoa ho laola ho lokolloa ha lithethefatsi, ho pata litatso tse sa thabiseng, le ho sireletsa metsoako e hlokolosi hore e se ke ea senyeha. Ho eketsoa ha joala ba 3,5-di-tert-butyl-4-hydroxybenzyl ho liaparo tsena ho fana ka botsitso le tšireletso e eketsehileng, ka hona ho matlafatsa ts'ebetso ea bona. Ka lebaka leo, tlhokahalo ea motsoako ona e ntse e eketseha, haholo-holo United States le Europe, moo melao e thata le litekanyetso tsa boleng li tsamaisang tlhokahalo ea lisebelisoa tse phahameng tsa ts'ebetso.

 

Litlhaloso tsa 'Maraka oa Libaka

 

Kua United States, mmaraka wa dihlare ke o mongwe wa mebaraka e megolo kudu lefaseng, yeo e gatelelago kudu popontšhwa le boleng. Tšebeliso ea theknoloji e tsoetseng pele ea ho roala e ntse e ata haholo, 'me bahlahisi ba ntse ba batla li-additives tse atlehang ho ntlafatsa mekhoa ea bona. Mokhoa o ntseng o hola oa meriana e etselitsoeng motho ka mong le nts'etsopele ea lits'ebetso tse rarahaneng tsa phepelo ea lithethefatsi li ntse li tsoela pele ho tsamaisa tlhokahalo ea li-additives tse khethehileng joalo ka 3,5-di-tert-butyl-4-hydroxybenzyl joala.

 

Ka mokhoa o ts'oanang, Europe, indasteri ea meriana e tšoauoa ka moralo o tiileng oa taolo o etelletsang pele polokeho ea mokuli le katleho ea sehlahisoa. European Medicines Agency (EMA) e thehile litataiso tsa ho khothaletsa tšebeliso ea li-excipients tsa boleng bo holimo le li-additives mefuteng ea meriana. Ka hona, 'maraka oa li-additives tsa litlhare tse kenyelletsang 3,5-di-tert-butyl-4-hydroxybenzyl joala o lebelletsoe ho paka kholo e kholo lilemong tse tlang.

 

Maikutlo a Bokamoso

 

E le tlatsetso ea ho roala meriana, litebello tsa kamoso tsa 'maraka oa joala oa 3,5-di-tert-butyl-4-hydroxybenzyl lia ts'episa. Ka boikitlaetso bo tsoelang pele ba lipatlisiso le nts'etsopele e reretsoeng ho ntlafatsa mekhoa ea phepelo ea lithethefatsi, tlhoko ea li-stabilizers le li-preservatives e kanna ea eketseha. Ho feta moo, tlhokomeliso e ntseng e eketseha har'a bareki le litsebi tsa tlhokomelo ea bophelo mabapi le bohlokoa ba boleng ba sehlahisoa le polokeho ho tla tsoela pele ho khanna ho amoheloa ha li-additives tse sebetsang hantle mefuteng ea meriana.

 

Ka kakaretso, 3,5-di-tert-butyl-4-hydroxybenzyl joala (CAS 88-26-6) e lebelletsoe ho phetha karolo ea bohlokoa indastering ea meriana, haholo-holo e le tlatsetso ea ho roala. Bokhoni ba eona ba ho matlafatsa botsitso le katleho ea metsoako ea meriana bo etsa hore e be karolo ea bohlokoa ho nts'etsopele ea mekhoa e tsoetseng pele ea ho fana ka meriana. Ha 'maraka o ntse o tsoela pele ho fetoha, ba amehang indastering ea meriana ba lokela ho beha leihlo ka hloko mekhoa le mekhoa e mecha e amanang le motsoako ona ho sebelisa melemo ea eona ka katleho.


Nako ea poso: Nov-05-2024