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sehlahisoa

N-(tert-Butoxycarbonyl)glycylglycine (CAS# 31972-52-8)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule C9H16N2O5
'Misa oa Molar 232.23
Botenya 1.222±0.06 g/cm3(E boletsoeng esale pele)
Melting Point 132 °C
Boling Point 488.1±30.0 °C(E boletsoeng esale pele)
Flash point 249°C
Solubility e qhibilihang ka har'a Methanol
Khatello ea Mouoane 7.32E-11mmHg ho 25°C
Ponahalo Phofo
Mmala Bosoeu
pKa 3.41±0.10(E boletsoeng esale pele)
Boemo ba polokelo E tiisitsoe ka sehatsetsing, ka tlas'a -20°C
Refractive Index 1.483

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Likhoutu tsa Kotsi 43 - E ka baka ts'oaetso ka ho kopana le letlalo
Tlhaloso ea Tšireletseho S24/25 - Qoba ho kopana le letlalo le mahlo.
S36/37 - Apara liaparo tse loketseng tsa tšireletso le liatlana.
Sehlopha sa Likotsi TS'OALANG

 

Selelekela

Boc-Gly-Gly-OH, e tsejoang e le Boc-Gly-Gly-OH(N-tert-butyloxycarbonyl-glycyl-glycine, Boc-Gly-Gly-OH ka bokhutšoanyane), ke ntho ea lik'hemik'hale. E latelang ke tlhaloso ea sebopeho sa eona, ts'ebeliso, tokiso le tlhaiso-leseling ea polokeho:

 

1. Tlhaho:

Boc-Gly-Gly-OH ke 'mala o mosoeu ho isa ho o mosoeu o nang le ntlha e phahameng ea ho qhibiliha le ho qhibiliha ho tlase. E tsitsitse mocheso oa kamore, empa e ka senyeha tlas'a mocheso o phahameng, mahlaseli a letsatsi kapa tikoloho e mongobo.

 

2. Sebelisa:

Boc-Gly-Gly-OH ke sehlopha se sebelisoang hangata se sireletsang amino acid. E sebelisetsoa ho sireletsa sehlopha sa amino sa glycylglycine ka lik'hemik'hale tsa lik'hemik'hale ho qoba karabelo ea eona ea lehlakoreng karabelong ea lik'hemik'hale. Nakong ea tlhahiso ea polypeptide kapa protheine, Boc-Gly-Gly-OH e ka eketsoa e le sehlopha se sireletsang ebe e tlosoa tlas'a maemo a loketseng ho lumella ketane ea polypeptide hore e atolosoe.

 

3. Mokhoa oa ho itokisa:

Ho lokisoa ha Boc-Gly-Gly-OH hangata ho etsoa ka mekhoa ea organic synthesis. Mokhoa o mong o tloaelehileng oa ho lokisa ke ho sebetsana le lihlopha tse peli tsa hydroxyl tsa glycine ka thoko le Boc-anhydride (tert-butyloxycarbonyl anhydride) ho theha Boc-Gly-Gly-OH. Maemo a karabelo a hloka ho laoloa nakong ea tokiso ho netefatsa chai le bohloeki.

 

4. Litaba tsa Polokeho:

Boc-Gly-Gly-OH e batla e bolokehile tlasa maemo a laboratori ka kakaretso, empa lintlha tse latelang li ntse li hloka ho eloa hloko:

-Motsoako ona o ka baka ho halefisoa ke letlalo, mahlo le pampiri ea ho hema, kahoo sebelisa mehato e hlokahalang ea tšireletso e kang li-gloves tsa laboratori le likhalase ha li pepesitsoe.

- Qoba ho kopana le li-oxidants kapa lintho tse tukang nakong ea tšebeliso kapa polokelo ho qoba maemo a kotsi a kang mollo kapa ho phatloha.

- Ts'ebetso e nepahetseng le ho lahla metsoako e setseng le litšila ka laboratoring, ho latela mekhoa le melaoana e sireletsehileng ea hona joale.

 


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