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N-tert-Butoxacarbonyl-O-benzyl-L-threonine (CAS# 15260-10-3)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule C16H23NO5
'Misa oa Molar 309.36
Botenya 1.152±0.06 g/cm3(E boletsoeng esale pele)
Melting Point 80-82°C(lebone)
Boling Point 461.5±45.0 °C(E boletsoeng esale pele)
Phetoho e khethehileng(α) 22 º (c=2 ho 95% ethanol)
Flash point 187.9°C
Khatello ea Mouoane 1.36E-07mmHg ho 25°C
Ponahalo Phofo ea kristale e tšoeu ho isa bosoeu
Mmala Bosoeu ho isa ho Ho batla ho tšoeu
BRN 3065591
pKa 3.50±0.10(E boletsoeng esale pele)
Boemo ba polokelo Boloka sebakeng se lefifi, se tiisitsoe moo ho omileng, Mocheso oa Kamore
Refractive Index 16.5 ° (C=1, MeOH)

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Selelekela
N-Boc-O-benzyl-L-threonine ke motsoako oa lintho tse phelang. Se latelang ke selelekela sa sebopeho sa eona, ts'ebeliso, mokhoa oa tlhahiso le tlhaiso-leseling ea polokeho:

Boleng:
N-Boc-O-benzyl-L-threonine ke kristale e tiileng e tšoeu kapa e sa bosoeu, e qhibilihang ka har'a lihlapolli tse tloaelehileng tse kang ethanol, dimethylformamide, chloroform, joalo-joalo.

Sebelisa:
N-Boc-O-benzyl-L-threonine ke karolo e bohareng ea bohlokoa ho organic synthesis 'me hangata e sebelisoa ha ho etsoa li-peptide le liprotheine. E ka sebelisoa e le sehlopha se sireletsang ka mokhoa o tiileng oa motsoako, motsoako oa motsoako oa metsi le motsoako oa ethanolamine-mediated ho thibela karabelo e ka thōko ea threonine ts'ebetsong ea ho itšoara, e le ho ntlafatsa khetho le chai ea karabelo.

Mokhoa:
Tokisetso ea N-Boc-O-benzyl-L-threonine hangata e etsoa ke metsoako ea lik'hemik'hale. Threonine e acylated ka N-tert-butoxycarbonyl (Boc-O-benzyl) 'me li-activator tse kang N,N-disopropylethylamine (DIPEA) kapa carbodiimide (DCC) lia eketsoa. Ka mor'a karabelo, N-Boc-O-benzyl-L-threonine e ile ea fumanoa.

Lintlha tsa Tšireletseho:
N-Boc-O-benzyl-L-threonine e na le ts'ireletso e phahameng ea tšireletso, empa e le motsoako oa manyolo, mehato e latelang ea tšireletso e ntse e lokela ho hlokomeloa: qoba ho kopana le letlalo, mahlo le tsamaiso ea ho hema; Apara liatlana tse sireletsang, likhalase le limaske ha u sebetsa; Sebetsa ka laboratoring e nang le moea o motle; Qoba ho kopana le li-oxidants le acid ha u li boloka. Haeba e ts'oaroe ka phoso kapa e hema, e lokela ho hlatsuoa kapa ho phekoloa ka tlhokomelo ea bongaka ka nako.


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