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N-Fmoc-N'-trityl-L-histidine (CAS# 109425-51-6) Setšoantšo se Tletseng
  • N-Fmoc-N'-trityl-L-histidine (CAS# 109425-51-6) 1

N-Fmoc-N'-trityl-L-histidine (CAS# 109425-51-6)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule C40H33N3O4
'Misa oa Molar 619.71
Botenya 1.24±0.1 g/cm3(E boletsoeng esale pele)
Melting Point 150-155°C(lebone)
Boling Point 811.7±65.0 °C(E boletsoeng esale pele)
Phetoho e khethehileng(α) +86.0 °(D/25)(c=5%inCHCl3)
Flash point 444.7°C
Ho qhibiliha ha Metsi E qhibiliha hanyane ka metsing.
Khatello ea Mouoane 7.59E-28mmHg ho 25°C
Ponahalo Lense e tšoeu
Mmala Bosoeu ho isa bosoeu
BRN 5204720
pKa 3.06±0.10(E boletsoeng esale pele)
Boemo ba polokelo 2-8°C

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

E hlahisa N-Fmoc-N'-trityl-L-histidine (CAS # 109425-51-6), moaho oa premium bakeng sa synthesis ea peptide e etselitsoeng ho phahamisa merero ea hau ea lipatlisiso le nts'etsopele. Motsoako ona oa bohloeki bo phahameng ke sesebelisoa sa bohlokoa bakeng sa litsebi tsa k'hemistri le biochemist tse batlang ho theha li-peptide tse rarahaneng ka nepo le ka bokhabane.

N-Fmoc-N'-trityl-L-histidine ke mofuta o sirelelitsoeng oa amino acid histidine, e nang le lihlopha tse peli tsa Fmoc (9-fluorenylmethoxycarbonyl) le trityl tse sireletsang. Lihlopha tsena tse sireletsang li bohlokoa bakeng sa ho netefatsa botsitso le ts'ebetso ea amino acid nakong ea ts'ebetso ea ho kopanya. Sehlopha sa Fmoc se lumella ts'ireletso e bonolo tlas'a maemo a bonolo a motheo, ha sehlopha sa trityl se fana ka tšireletso e eketsehileng khahlanong le maikutlo a sa batleheng a lehlakoreng, e leng se etsang hore motsoako ona o be o loketseng bakeng sa solid-phase peptide synthesis (SPPS).

Ka foromo ea molek'hule ea C30H31N3O2 le boima ba molek'hule ea 469.59 g/mol, N-Fmoc-N'-trityl-L-histidine e bonts'a ho qhibiliha ho hoholo ha li-solvents tse tloaelehileng, ho nolofalletsa ho kenngoa ha eona ho liprothokhole tse fapaneng tsa maiketsetso. Sebopeho sa eona se ikhethang ha se matlafatse feela botsitso ba li-peptide tse hlahisoang empa hape se kenya letsoho mosebetsing oa tsona oa likokoana-hloko, e leng se etsang hore e be letlotlo la bohlokoa ho sibolloeng ha lithethefatsi le nts'etsopele.

Hore na o sebetsa ho li-peptide tsa kalafo, ho etsa lipatlisiso ho baeloji ea limolek'hule, kapa ho hlahloba mekhoa e mecha ea biochemistry, N-Fmoc-N'-trityl-L-histidine ke khetho e nepahetseng bakeng sa litlhoko tsa hau tsa motsoako. Sehlahisoa sa rona se etsoa tlas'a mehato e thata ea taolo ea boleng ho netefatsa boemo bo phahameng ka ho fetisisa ba bohloeki le botsitso, bo u lumellang ho tsepamisa maikutlo lipatlisisong tsa hau ka kholiseho.

Notlolla bokhoni ba merero ea hau ea ho kopanya peptide ka N-Fmoc-N'-trityl-L-histidine. Eba le phapang eo li-reagents tsa boleng bo holimo li ka e etsang ka laboratoring ea hau kajeno!

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