N-Cbz-L-Leucine(CAS# 2018-66-8)
Kotsi le Polokeho
| Matšoao a Kotsi | Xn - E Kotsi |
| Likhoutu tsa Kotsi | R10 – E ka cha R20/22 – E kotsi ka ho hema le haeba e koetsoe. R37/38 – E tenang tsamaiso ya ho hema le letlalo. R40 - Bopaki bo fokolang ba phello ea kankere R41 – Kotsi ya tshenyo e kgolo mahlong R36/37/38 – Ho tena mahlo, tsamaiso ya ho hema le letlalo. R20/21/22 – E kotsi ka ho hema, ho kopana le letlalo le ha e koetsoe. R67 – Mouoane o ka baka ho otsela le ho tsekela R63 – Kotsi e ka bang teng ya kotsi ho ngwana ya esong ho hlahe R19 - E ka etsa peroxides e phatlohang |
| Tlhaloso ea Tšireletseho | S16 - Ipoloke hole le mehloli ea mollo. S26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka. S36/37/39 - Apara liaparo tse loketseng tsa tšireletso, liatlana le tšireletso ea mahlo / sefahleho. S45 – Ha ho ka etsahala kotsi kapa ha o ikutlwa o sa phele hantle, batla keletso ya bongaka hanghang (bontsha leibole neng kapa neng ha ho kgoneha.) S36 - Apara liaparo tse loketseng tsa tšireletso. S36/37 - Apara liaparo tse loketseng tsa tšireletso le liatlana. S60 - Thepa ena le setshelo sa eona li tlameha ho lahloa e le litšila tse kotsi. |
| Li-ID tsa UN | UN 1993 3/PG 3 |
| WGK Jeremane | 3 |
| RTECS | OH2921000 |
| Khoutu ea HS | 29242990 |
N-Cbz-L-Leucine (CAS # 2018-66-8) selelekela
Cbz-L-leucine, lebitso le felletseng la Boc-L-leucine (Boc e emetse dibutoxycarbonyl sehlopha se sireletsang), ke motsoako oa amino acid. Se latelang ke selelekela sa sebopeho sa eona, tšebeliso, mekhoa ea tlhahiso le tlhaiso-leseling ea polokeho:
Boleng:
- Ponahalo: E tiileng ka kristale e tšoeu
- E qhibiliha ka har'a ethanol, dimethylformamide (DMF) le dichloromethane
Sebelisa:
- CBZ-L-Leucine ke sehlopha se atisang ho sebelisoa amino acid e sireletsang sehlopha sa hydroxyl ea leucine nakong ea tlhahiso ea li-peptide ho e thibela ho sebetsana le li-reactants tse ling. Ka peptide synthesis moo masala a mangata a leucine a hlokang ho hlahisoa, Cbz-L-leucine e ka sebelisoa ho sireletsa sehlopha sa hydroxyl sa leucine bakeng sa mekhoa e latelang ea synthesis.
- Leucine ke amino acid ea bohlokoa e phethang karolo ea bohlokoa sebopehong sa protheine le tšebetsong.
Mokhoa:
- Tokisetso ea Cbz-L-leucine hangata e fumanoa ka karabelo ea leucine le Boc-OSu (Boc—N-nitrocarbonyl-L-leucine). Karabelong eo, Boc-OSu e sebetsa joalo ka selelekela sa sehlopha se sireletsang mme e etsa karabelo ea esterification le leucine ho hlahisa Cbz-L-leucine.
Lintlha tsa Tšireletseho:
- Cbz-L-leucine ke k'hemik'hale 'me e lokela ho bolokoa ka nepo hole le ho khantša le li-oxidants.
- Nakong ea tšebeliso, qoba ho hema lerole la eona kapa ho kopana le letlalo le mahlo.
- Latela mekhoa e sireletsehileng ha u tšoara le ho boloka, 'me u apare lisebelisoa tse nepahetseng tsa ho itšireletsa tse kang liatlana tsa laborateng le tšireletso ea mahlo.
