N-Cbz-D-Tryptophan(CAS# 2279-15-4)
| Likhoutu tsa Kotsi | R22/22 - R36/37/38 – Ho tena mahlo, tsamaiso ya ho hema le letlalo. |
| Tlhaloso ea Tšireletseho | S22 - U se ke ua hema lerole. S24/25 - Qoba ho kopana le letlalo le mahlo. S44 - S35 - Thepa ena le setshelo sa eona li tlameha ho lahloa ka tsela e sireletsehileng. S28 - Ka mor'a ho kopana le letlalo, hlatsoa hang-hang ka sesepa-suds e ngata. S7 - Boloka setshelo se koetsoe ka thata. S4 - Ipoloke hole le libaka tsa bolulo. |
| Khoutu ea HS | 29339900 |
| Sehlopha sa Likotsi | MOQEBI |
Selelekela
N(^ a) -Benzyloxycarbonyl-D-tryptophan(N(^ a)-Benzyloxycarbonyl-D-tryptophan) ke lik'hemik'hale, tse tsejoang hape e le CBZ-D-Trp. E latelang ke tlhaloso ea sebopeho sa eona, tšebeliso, tlhahiso le tlhaiso-leseling ea polokeho:
Tlhaho:
N(^ a) -Benzyloxycarbonyl-D-tryptophan ke bosoeu ho isa ho bosehla bo tiileng ba kristale. E batla e tsitsitse mocheso oa kamore 'me e ka bolokoa nako e telele tlas'a maemo a anhydrous. Ha e qhibilihe ka metsing, empa e qhibiliha ka har'a metsoako e meng ea tlhaho e kang methanol le dimethyl sulfoxide.
Sebelisa:
N(^ a) -Benzyloxycarbonyl-D-tryptophan hangata e sebelisoa e le lihlopha tse sireletsang ka har'a organic synthesis, haholo-holo ka lik'hemik'hale tsa peptide synthesis. Tšebeliso ea eona e ka sehloohong ke e tsoang ho li-amino acid bakeng sa ho qaptjoa ha li-module tse itseng ka polypeptide kapa liketane tsa protheine. E ka phetha karolo ea bohlokoa ho kopanngoeng ha lithethefatsi tse ncha ka tsela ena.
Mokhoa:
Tokisetso ea N (^ a) -Benzyloxycarbonyl-D-tryptophan hangata e etsoa ke metsoako ea lik'hemik'hale. Ntlha ea pele, joala ea benzyl le carbon dioxide li itšoara ho etsa benzyloxycarboxylic acid, 'me joale amino acid tryptophan le benzyloxycarboxylic acid e etsoa esterified ho fumana sehlahisoa sa CBZ-D-Trp. Karabelo e hloka thuso ea li-catalyst tse ling tsa organic le solvents.
Lintlha tsa Tšireletseho:
N(^ a) -Benzyloxycarbonyl-D-tryptophan e na le boitsebiso bo fokolang ba tšireletso, empa ho latela boitsebiso bo fumanehang, hangata bo nkoa e le chefo. Ho pepeseha ha nako e telele kapa ho pepeseha ho feteletseng ho ka ba le litlamorao tse mpe tsa bophelo bo botle. Ka hona, mehato e loketseng ea tšireletso e tlameha ho nkoa ha ho sebelisoa, ho boloka le ho tšoara motsoako ona, ho kenyeletsa ho roala thepa e loketseng ea ho itšireletsa le ho sebetsana le tikoloho e nang le moea o motle. Ka nako e ts'oanang, hoa hlokahala ho latela mekhoa e nepahetseng ea ts'ebetso ea ts'ireletso le mekhoa ea ho lahla.
Ka kopo hlokomela hore sengoloa sena ke kakaretso feela ea kompone eo ho buuoang ka eona, mme kopo e ikhethileng le tlhahlobo ea kotsi li lokela ho etsoa tikolohong e itseng ea laboratori. Pele o sebelisa ntho leha e le efe ea lik'hemik'hale, ka kopo etsa bonnete ba hore u ithuta lintlha tse amehang ka botlalo 'me u buisane le setsebi esale pele.
