N-Cbz-D-Serine (CAS# 6081-61-4)
Tlhaloso ea Tšireletseho | S22 - U se ke ua hema lerole. S24/25 - Qoba ho kopana le letlalo le mahlo. |
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N-Benzyloxycarbonyl-D-serine(N-Benzyloxycarbonyl-D-serine) ke motsoako oa lintho tse phelang. E na le litšobotsi tse latelang:
Ponahalo: Hangata phofo e se nang 'mala kapa e tšoeu ea kristale.
Mokhoa oa molek'hule: C14H15NO5
Boima ba molek'hule: 285.28g/mol
Solubility: Ho qhibiliha ka har'a lihlapolli tse ling tsa tlhaho, joalo ka chloroform le methanol.
N-Benzyloxycarbonyl-D-serine hangata e sebelisoa e le li-intermediate bakeng sa ho kopanya le ho ithuta metsoako e meng. Ke ntho ea bohlokoa lefapheng la k'hemistri ea meriana le ea lintho tse bonahalang 'me e na le mefuta e mengata ea likopo.
Mokhoa o tloaelehileng oa ho lokisa N-Benzyloxycarbonyl-D-serine ke ka ho arabela D-serine ka N-benzyloxycarbonylchloromethane. Ntlha ea pele, D-serine e ile ea qhibiliha ka tharollo ea sodium bicarbonate, 'me joale N-benzyloxycarbonylchloromethane ea eketsoa. Ka mor'a hore karabelo e phethoe, sehlahisoa se ka hloekisoa ka ho eketsehileng ka ho se nke lehlakore ka tharollo ea acidic le ho ntšoa ho eketsehileng le crystallization.
Mabapi le tlhahisoleseling ea polokeho, chefo ea N-Benzyloxycarbonyl-D-serine e tlase, empa lintlha tse latelang li ntse li hloka ho hlokomeloa:
-Ena ke lik'hemik'hale 'me ho lokela ho nkoa tlhokomelo ho qoba ho kopana le letlalo, molomo le mahlo. Apara mehato e loketseng ea ho itšireletsa, joalo ka liatlana, likhalase tsa tšireletso le lijase tsa laboratori.
-Ha o tšoara kapa o sebelisoa, o lokela ho etsoa sebakeng se nang le moea o motle ho qoba ho hema kapa ho metsa ntho eo.
-Nakong ea ho boloka le ho tšoara, ts'ebetso e nepahetseng ea ts'ireletso ea laboratori le melao e lokela ho lateloa.
Pele o sebelisa N-Benzyloxycarbonyl-D-serine, ho khothaletsoa ho bala leqephe la eona le nepahetseng la lintlha tsa polokeho le litaelo tsa polokeho ea thepa ka botlalo ho netefatsa ts'ebetso e bolokehileng.