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sehlahisoa

N-Cbz-D-glutamic acid alpha-benzyl ester (CAS# 65706-99-2)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule C20H21NO6
'Misa oa Molar 371.38
Botenya 1.268±0.06 g/cm3(E boletsoeng esale pele)
Melting Point 98.0 ho isa ho 102.0 °C
Boling Point 594.3±50.0 °C(E boletsoeng esale pele)
Phetoho e khethehileng(α) +22.0 ho ea ho +25.0 deg(C=1, MeOH)
Flash point 313.2°C
Solubility E qhibiliha ka methanol le acetic acid.
Khatello ea Mouoane 5.72E-15mmHg ho 25°C
Ponahalo Phofo ea kristale
Mmala Bosoeu ho isa bosoeu
BRN 5305848
pKa 4.47±0.10 (E boletsoeng esale pele)
Boemo ba polokelo E tiisitsoe ka ho omme, Mocheso oa Kamore
Refractive Index 1.575
MDL MFCD00069647

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Tlhaloso ea Tšireletseho 24/25 - Qoba ho kopana le letlalo le mahlo.
WGK Jeremane 3
Khoutu ea HS 29242990

 

Selelekela

ZD-glutamic acid 1-benzyl ester ke motsoako oa lintho tse phelang. E latelang ke tlhaloso ea sebopeho sa eona, tšebeliso, tlhahiso le tlhaiso-leseling ea polokeho:

 

Tlhaho:

-Ponahalo: Motsoako ke kristale e tšoeu kapa phofo ea kristale.

-Solubility: E qhibiliha ka har'a metsoako e meng ea tlhaho, joalo ka ethanol, dimethyl sulfoxide le chloroform.

- Sebaka se qhibilihang: Sebaka se qhibilihang sa motsoako ke hoo e ka bang likhato tse 145-147 tsa Celsius.

- Foromo ea molek'hule: C16H19NO5

- Boima ba 'mele: 309.33

-Sebopeho: E na le lihlopha tsa benzyl le amino acid.

 

Sebelisa:

-Chemical reagent: Ka organic synthesis, e ka sebelisoa e le reagent ea lik'hemik'hale, haholo-holo e loketseng motsoako oa li-amino acid.

- Lipatlisiso tsa lithethefatsi: Phuputsong ea lithethefatsi, e sebelisoa e le selelekela sa lithethefatsi tse khahlanong le hlahala, kapa se sebelisetsoa ho ithuta kinase inhibitors.

 

Mokhoa oa ho itokisa:

ZD-glutamic acid 1-benzyl ester e ka lokisoa ka mehato e latelang:

1. Benzyl joala le dimethyl carbamate li itšoara tlas'a maemo a alkaline ho hlahisa benzylethanolamine.

2. esterification ea benzylethanolamine e nang le D-glutamic acid e ka fumana ZD-glutamic acid 1-benzyl ester.

 

Lintlha tsa Tšireletseho:

-Motsoako o hloka ho ts'oaroa le ho sebelisoa ka mehato e nepahetseng ea ts'ireletso ea laboratori.

- Qoba ho kopana le letlalo, mahlo le tsela ea ho hema.

- Sebelisa lisebelisoa tsa ho itšireletsa tse kang lijase tsa lab, liatlana le likhalase tse sireletsang.

-E lokela ho sebetsoa sebakeng se nang le moea o motle ho qoba ho hema lerole kapa mouoane oa eona.

-Latela mekhoa e nepahetseng ea ho lahlela litšila ho qoba tšilafalo ea tikoloho.


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