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sehlahisoa

N-Boc-trans-4-Hydroxy-L-proline methyl ester (CAS# 74844-91-0)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule C11H19NO5
'Misa oa Molar 245.27
Botenya 1.216±0.06 g/cm3(E boletsoeng esale pele)
Melting Point 92-96 °C (hote.)
Boling Point 132°C/0.05mmHg(lit.)
Phetoho e khethehileng(α) -65 º (c=1 CHCl3)
Flash point 156.55°C
Solubility E qhibiliha ka chloroform, dichloromethane le ethyl acetate.
Khatello ea Mouoane 0mmHg ho 25°C
Ponahalo Crystal
Mmala E tšoeu ho isa ho beige e khanyang
pKa 14.27±0.40 (E boletsoeng esale pele)
Boemo ba polokelo Boloka sebakeng se lefifi, se tiisitsoe moo ho omileng, Mocheso oa Kamore
Refractive Index 1.501
MDL MFCD00076981

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Matšoao a Kotsi Xn - E Kotsi
Likhoutu tsa Kotsi R20/21/22 – E kotsi ka ho hema, ho kopana le letlalo le haeba e koetsoe.
R36/37/38 – Ho tena mahlo, tsamaiso ya ho hema le letlalo.
Tlhaloso ea Tšireletseho S24/25 - Qoba ho kopana le letlalo le mahlo.
S36 - Apara liaparo tse loketseng tsa tšireletso.
S26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka.
WGK Jeremane 3
Khoutu ea HS 29339900
Sehlopha sa Likotsi TS'OALANG

 

Selelekela

N-BOC-trans-4-hydroxy-L-proline methyl ester, lebitso le feletseng N-tert-butoxycarbonyl-trans-4-hydroxy-L-proline methyl ester, ke motsoako oa lintho tse phelang.

 

Boleng:

N-BOC-trans-4-hydroxy-L-proline methyl ester ke kristale e tšoeu e tiileng.

 

Sebelisa:

N-BOC-trans-4-hydroxy-L-proline methyl ester e atisa ho sebelisoa e le sehlopha se sireletsang amino acid ho organic synthesis chemistry. E ka sebelisoa e le sehlopha se sireletsang se sebetsang hantle ho sireletsa lihlopha tse sebetsang tsa hydroxyl ka har'a li-amino acid ho thibela liketso tse sa batleheng ho kopanngoa.

 

Mokhoa:

Tokisetso ea N-BOC-trans-4-hydroxy-L-proline methyl ester hangata e fumanoa ka ho arabela N-BOC-4-hydroxy-L-proline ka methanol. N-BOC-4-hydroxy-L-proline e sebetsanoa le activator (e kang DCC kapa DIC) ho etsa activated ester, ebe methanol e eketsoa ho itšoara le eona ho hlahisa N-BOC-trans-4-hydroxy- L-proline methyl ester. Sehlahisoa se lebisitsoeng se fumanoa ka crystallization kapa mekhoa e meng ea ho arohana le ho hloekisa.

 

Tlhahisoleseding ea Tšireletseho: Ha ho tluoa tabeng ea motsoako oa lik'hemik'hale, tšebeliso ea lisebelisoa le maemo a liteko li lokela ho ba le phihlelo e lumellanang ea tekheniki. Ts'ebetsong ea laboratori, tlhokomelo e lokela ho nkoa ho qoba ho kopana ka ho toba le letlalo le mahlo, le ho boloka moea o motle. Haeba u utloa bohloko leha e le bofe 'meleng kapa lintho tse ling tse sa thabiseng, u lokela ho ea ngakeng hang-hang.


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