N-Boc-N'-xanthyl-L-asparagine (CAS# 65420-40-8)

Selelekela

N(alpha)-boc-N(gamma)-(9-xanthenyl)-L-asparagine ke motsoako oa tlhaho o sebelisoang haholo mafapheng a biochemistry le chemistry ea meriana. E latelang ke tlhaloso ea sebopeho sa eona, ts'ebeliso, tokiso le tlhaiso-leseling ea polokeho:

Tlhaho:

N(alpha)-boc-N(gamma)-(9-xanthenyl)-L-asparagine ke kristale e tiileng. E na le 'mala o mosoeu kapa o mosehla' me e qhibiliha ka har'a metsoako ea tlhaho e kang dimethylformamide (DMF) le dichloromethane. E batla e tsitsitse mocheso oa kamore, empa e tla bola tlas'a mocheso o phahameng kapa maemo a matla a alkali.

Sebelisa:

N(alpha)-boc-N(gamma)-(9-xanthenyl)-L-asparagine e na le bohlokoa ba tšebeliso ea bohlokoa lipatlisisong tsa lithethefatsi. E ka sebelisoa ha ho etsoa litlhare tsa peptide, joalo ka lithethefatsi tse khahlanong le hlahala le metsoako ea bioactive peptide precursor. Ntle le moo, e ka sebelisoa e le sesebelisoa sa ho etsa lipatlisiso ho baeloji ea lik'hemik'hale ho lekola sebopeho le tšebetso ea liprotheine kapa li-peptide tse itseng.

Mokhoa oa ho itokisa:

Tokisetso ea N(alpha)-boc-N(gamma)-(9-xanthenyl)-L-asparagine ka kakaretso e kenyelletsa karabelo ea mehato e mengata. Ntlha ea pele, ea pele ea lipakeng e ile ea fumanoa ka karabelo ea condensation ea synthetic aspartic acid-4, 4 '-disopropylamino ester e nang le p-aminobenzoic acid. Ka mor'a moo, nucleophilic substitution reaction e sebelisoa ho hlahisa nylon ea oxyanthryl bohareng ho etsa sehlahisoa sa ho qetela.

Lintlha tsa Tšireletseho:

N(alpha)-boc-N(gamma)-(9-xanthenyl)-L-asparagine ke organic synthesis reagent,' me ts'ebetso ea eona e nepahetseng e hloka ho latela melao e akaretsang ea polokeho ea laboratori. Ka lebaka la khaello ea lintlha tse felletseng tse tsoang lithutong tsa chefo ea motsoako ona, tsebo ea likotsi tse ka bang teng e fokotsehile. Nakong ea ho ts'oaroa le ho sebelisoa, tlhokomelo e lokela ho nkoa ho qoba ho kopana ka ho toba le letlalo le mahlo, le ho qoba ho hema phofo kapa khase ea eona. Ho netefatsa polokeho, ho kgothaletswa ho sebetsa ka laboratoring le ho e sebelisa ho latela melao ea lisebelisoa tsa ts'ireletso ea motho.