N-Boc-N'-trityl-L-glutamine (CAS# 132388-69-3)

WGK Jeremane	3
Khoutu ea HS	29242990

N-Boc-N '-trityl-L-glutamine (N-Boc-N'-trityl-L-glutamine, e khutsufalitsoeng e le Boc-Gln(Trt)-OH) ke motsoako oa lintho tse phelang. E na le litšobotsi tse latelang:1. Ponahalo: phofo e tšoeu ea kristale.
2. foromo ea molek'hule: C39H35N3O6
3. Boima ba molek'hule: 641.71g / mol
4. Sebaka se qhibilihang: 148-151°C
5. Solubility: Ho qhibiliha ka har'a metsoako e mengata ea lintho tse phelang, tse kang dimethyl sulfoxide (DMSO) le dichloromethane.
6. Botsitso: e batlang e tsitsitse tlas'a maemo a tloaelehileng a liteko.

Ka motsoako oa lik'hemik'hale, N-Boc-N '-trityl-L-glutamine hangata e sebelisoa e le sehlopha se sireletsang amino acid kapa bohareng. Lisebelisoa tsa eona tsa mantlha li kenyelletsa:

1. e sebelisoang e le sehlopha se sireletsang glutamine ka peptide le protheine synthesis.
2. Phuputsong ea lithethefatsi tsa maiketsetso, e sebelisetsoa ho etsa li-analogue tsa glutamine.
3. e sebelisoang e le sebaka sa mahareng ho kopanya metsoako e meng ea tlhaho.

Mokhoa oa ho lokisa N-Boc-N '-trityl-L-glutamine hangata o tjena:

1. Ntlha ea pele, itšoara ka N-protected glutamine (e kang N-Boc-L-glutamine) le trityl halide (e kang trityl chloride) ho fumana N-Boc-N '-trityl-L-glutamine.

Lintlha tsa Tšireletseho:
N-Boc-N '-trityl-L-glutamine, joalo ka motsoako oa lintho tse phelang, e batla e bolokehile tlas'a tšebeliso e nepahetseng le polokelo. Leha ho le joalo, lintlha tse latelang li ntse li lokela ho hlokomeloa:

1. Qoba ho kopana le mahlo, letlalo le tsela ea ho hema. Sebelisa liatlana tse sireletsang lik'hemik'hale le likhalase.
2. Boloka sebakeng se omileng, se phodileng.
3. Latela mekhoa ea tšireletso 'me u tšoare hantle le ho lahla litšila tsa motsoako.