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sehlahisoa

N-Carbobenzyloxy-L-proline(CAS# 1148-11-4)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule C13H15NO4
'Misa oa Molar 249.26
Botenya 1.1952 (khakanyo e fosahetseng)
Melting Point 75-77°C
Boling Point 392.36°C (khakanyo e boima)
Phetoho e khethehileng(α) -60 º (c=2,AcOH)
Flash point 215.3°C
Solubility Solubility ka methanol, hoo e batlang e le pepeneneng.
Khatello ea Mouoane 3.06E-08mmHg ho 25°C
Ponahalo Likristale tse tšoeu ho isa ho tse mosehla o khanyang
Mmala Bosoeu ho isa bosoeu
BRN 88579
pKa 3.99±0.20(E boletsoeng esale pele)
Boemo ba polokelo E tiisitsoe ka ho omme, Mocheso oa Kamore

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Cbz-L-Proline, eo lebitso la eona le felletseng e leng L-Proline-9-Butyroyl Ester, ke motsoako oa manyolo. Se latelang ke selelekela sa thepa, tšebeliso, mekhoa ea ho lokisa le tlhaiso-leseling ea polokeho ea Cbz-L-proline:

Boleng:
- Ponahalo: Phofo e tšoeu ea crystalline kapa crystalline.
- Ho qhibiliha ha letsoai: ho qhibiliha ka har'a asiti, ha ho qhibilihe ka metsing.

Sebelisa:
- Cbz-L-proline e atisa ho sebelisoa e le sehlopha se sireletsang ho organic synthesis ho sireletsa lihlopha tsa amino (NH₂) ka amino acid.
- E sebelisoa haholo ho kopantseng lik'hemik'hale tsa li-peptide le liprotheine.

Mokhoa:
Tokisetso ea Cbz-L-proline hangata e etsoa ka mehato e latelang:
1. Proline e sebetsana le chloroformate-9-butyl ester tlas'a maemo a alkaline ho fumana substrate.
2. Substrate e tšoaroa tlas'a maemo a acidic ho hlahisa Cbz-L-proline.

Lintlha tsa Tšireletseho:
- Cbz-L-Proline ke k'hemik'hale 'me e lokela ho tšoaroa ka hloko. Hlokomela ho qoba ho kopana le letlalo le mahlo, 'me u qobe ho hema.
- Apara lisebelisoa tsa ts'ireletso tse nepahetseng joalo ka liatlana tsa lab le likhalase ha u sebelisoa.
- Boloka e tiisitsoe ka thata 'me u qobe mahlaseli a letsatsi le mocheso o phahameng.
- Kamora ho sebelisoa le ho ts'oaroa, latela melao ea lehae ea ho lahla lik'hemik'hale.


  • E fetileng:
  • E 'ngoe:

  • Ngola molaetsa wa hao mona mme o re romele wona