N-Carbobenzyloxy-L-proline(CAS# 1148-11-4)
Cbz-L-Proline, eo lebitso la eona le felletseng e leng L-Proline-9-Butyroyl Ester, ke motsoako oa manyolo. Se latelang ke selelekela sa thepa, tšebeliso, mekhoa ea ho lokisa le tlhaiso-leseling ea polokeho ea Cbz-L-proline:
Boleng:
- Ponahalo: Phofo e tšoeu ea crystalline kapa crystalline.
- Ho qhibiliha ha letsoai: ho qhibiliha ka har'a asiti, ha ho qhibilihe ka metsing.
Sebelisa:
- Cbz-L-proline e atisa ho sebelisoa e le sehlopha se sireletsang ho organic synthesis ho sireletsa lihlopha tsa amino (NH₂) ka amino acid.
- E sebelisoa haholo ho kopantseng lik'hemik'hale tsa li-peptide le liprotheine.
Mokhoa:
Tokisetso ea Cbz-L-proline hangata e etsoa ka mehato e latelang:
1. Proline e sebetsana le chloroformate-9-butyl ester tlas'a maemo a alkaline ho fumana substrate.
2. Substrate e tšoaroa tlas'a maemo a acidic ho hlahisa Cbz-L-proline.
Lintlha tsa Tšireletseho:
- Cbz-L-Proline ke k'hemik'hale 'me e lokela ho tšoaroa ka hloko. Hlokomela ho qoba ho kopana le letlalo le mahlo, 'me u qobe ho hema.
- Apara lisebelisoa tsa ts'ireletso tse nepahetseng joalo ka liatlana tsa lab le likhalase ha u sebelisoa.
- Boloka e tiisitsoe ka thata 'me u qobe mahlaseli a letsatsi le mocheso o phahameng.
- Kamora ho sebelisoa le ho ts'oaroa, latela melao ea lehae ea ho lahla lik'hemik'hale.