N-Benzyloxycarbonyl-L-asparagine (CAS# 2304-96-3)
| Likhoutu tsa Kotsi | R20/21/22 – E kotsi ka ho hema, ho kopana le letlalo le ha e koetsoe. R36/37/38 – Ho tena mahlo, tsamaiso ya ho hema le letlalo. |
| Tlhaloso ea Tšireletseho | S24/25 - Qoba ho kopana le letlalo le mahlo. S36 - Apara liaparo tse loketseng tsa tšireletso. S26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka. |
| WGK Jeremane | 3 |
| TSCA | Ee |
| Khoutu ea HS | 29242990 |
| Sehlopha sa Likotsi | TS'OALANG |
Selelekela
N-benzyloxycarbonyl-L-asparagine ke motsoako oa lintho tse phelang.
Boleng:
N-benzyloxycarbonyl-L-asparagine ke kristale e tšoeu e tiileng e qhibilihang ka har'a ethanol, ether le dimethylformamide 'me e qhibiliha hanyenyane metsing. Ke motsoako oa amide o nang le lihlopha tse peli tse sebetsang, joala ba amide le benzyl.
Lits'ebetsong tse sebetsang, N-benzyloxycarbonyl-L-asparagine e sebelisoa haholo-holo e le karolo e bohareng ea motsoako oa metsoako ea tlhaho. E na le botsitso bo botle le ts'ebetso e ntle, 'me e ka kenya letsoho liketsong tse fapaneng tsa lik'hemik'hale, joalo ka karabelo ea li-substitution, phokotso le karabelo e matla.
Synthesis ea N-benzyloxycarbonyl-L-asparagine e ka fumanoa ka karabelo ea joala ea benzyl le L-asparagine. Mokhoa o sebelisoang hangata ke ho arabela joala ba benzyl le L-asparagine tlas'a maemo a alkaline ho hlahisa sehlahisoa se lebisitsoeng.
Tlhahisoleseding ea polokeho: N-benzyloxycarbonyl-L-asparagine e na le botsitso bo botle tlas'a maemo a tloaelehileng, empa ho ntse ho hlokahala ho hlokomela hore e chefo. Ha u sebetsa, apara lisebelisoa tse loketseng tsa ho itšireletsa 'me u qobe ho kopana ka ho toba le letlalo le mahlo. Ha u boloka le ho tšoara, mehloli ea mollo le mocheso o phahameng o lokela ho qojoa. E lokela ho bolokoa sebakeng se omeletseng, se nang le moea o motle, hole le li-oxidizing agents le li-acid tse matla le metheo. Boemong ba maemo a sa lebelloang a kang ho ama letlalo kapa ho hema, ho lokela ho batloa tlhokomelo ea bongaka hang-hang.
