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sehlahisoa

N-alpha-Cbz-L-lysine(CAS# 2212-75-1)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule Setšoantšo sa C14H20N2O4
'Misa oa Molar 280.32
Botenya 1.206±0.06 g/cm3(E boletsoeng esale pele)
Melting Point 226-231°C (Dec.)(lit.)
Boling Point 497.0±45.0 °C(E boletsoeng esale pele)
Phetoho e khethehileng(α) -13 º (c=2 ho 0.2N HCl)
Solubility Methanol (Hanyenyane), Metsi (Hanyenyane)
Ponahalo Tiileng
Mmala Bosoeu
BRN 2153826
pKa 3.90±0.21(E boletsoeng esale pele)
Boemo ba polokelo Lula sebakeng se lefifi, sepakapaka se se nang moea, mocheso oa kamore
E hloahloa E utloang mocheso
Refractive Index 1,512
MDL MFCD00038204
Sebelisa E sebelisoa bakeng sa ho lokisetsa ho bonolo ha L-α-aminoadipic acid.

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Matšoao a Kotsi Xn - E Kotsi
Likhoutu tsa Kotsi R20/21/22 – E kotsi ka ho hema, ho kopana le letlalo le ha e koetsoe.
R36/37/38 – Ho tena mahlo, tsamaiso ya ho hema le letlalo.
Tlhaloso ea Tšireletseho S22 - U se ke ua hema lerole.
S24/25 - Qoba ho kopana le letlalo le mahlo.
S36 - Apara liaparo tse loketseng tsa tšireletso.
S26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka.
WGK Jeremane 3
TSCA Ee
Khoutu ea HS 29242990

 

Selelekela

CBZ-L-lysine, ka lik'hemik'hale tse tsejoang e le Nn-butylcarboyl-L-lysine, ke sehlopha se sireletsang amino acid.

 

Boleng:

CBZ-L-lysine ke phofo e tiileng, e se nang mebala kapa e tšoeu ea kristale e nang le botsitso bo phahameng ba mocheso. E qhibiliha habonolo ka har'a metsoako ea tlhaho e kang chloroform le dichloromethane.

 

CBZ-L-lysine e sebelisoa haholo ho organic synthesis ka ho sireletsa lihlopha tse sebetsang tsa amino tsa lysine. Ho sireletsa sehlopha se sebetsang sa amino sa lysine ho thibela karabelo ea eona ea lehlakore nakong ea ho kopanya.

 

CBZ-L-lysine hangata e fumanoa ka acylation ea L-lysine. Li-reagents tsa acylation tse sebelisoang ka tloaelo li kenyelletsa chloroformyl chloride (COC1) le phenylmethyl-N-hydrazinocarbamate (CbzCl), e ka etsoang ka metsoako ea tlhaho ka mocheso o loketseng le maemo a pH.

Ha ho lahla litšila le tharollo bakeng sa motsoako ona, mekhoa e nepahetseng ea ho lahla e lokela ho amoheloa 'me ho lateloe melao e nepahetseng ea tšireletso.


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