Methoxymethyl triphenylphosphonium chloride (CAS# 4009-98-7)
Selelekela
Lisebelisoa
(Methoxymethyl) triphenylphosphorus chloride e sebelisoa ho etsa synthesize cefaltacin, e leng sethethefatsi se thibelang kokoana-hloko le se thibelang hlahala. E boetse e sebelisoa ho etsa sekhechana sa paclitaxel.
Tokisetso
Mokhoa oa ho kopanya (methoxymethyl) triphenylphosphine chloride, e nang le mehato e latelang: tlas'a tšireletso ea naetrojene, ho eketsa 50mL ea anhydrous acetone ho reactor, ebe o eketsa 32g ea triphenylphosphine, e tsosang le ho phahamisa mocheso ho 37 ° C, ho boloka mocheso o sa khaotseng. , ho eketsa 20g ea methyl chloromethyl ether ho reactor, ebe e arabela ho 37 ° C bakeng sa 3h, butle-butle ho phahamisa mocheso ho 47 ° C ka tekanyo ea 1 ° C / min, karabelo e ile ea tsoela pele bakeng sa 3h, karabelo e ile ea emisoa, 'me 37.0g (methoxymethyl) triphenylphosphorus chloride e ile ea fumanoa ka ho hloekisa, anhydric. ether ho hlatsoa le ho omisa ka lihlahisoa tsa 88.5%.
