Metadoxine (CAS# 74536-44-0)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule	C8H11NO3.C5H7NO3
'Misa oa Molar	298.293
Melting Point	102-104°C
Solubility	DMSO (Hanyane), Methanol (Hanyenyane)
Ponahalo	Tiileng
Mmala	Bosoeu ho isa Bosehla bo Khanyang
Boemo ba polokelo	E koaletsoe sebakeng se omileng, 2-8 ° C
Sebelisa	Boikemisetso ba litaba ka HPLC
Thuto ea in vitro	Kalafo ea Metadoxine ka nako e le 'ngoe e thibela karohano ea adipogenic ka mokhoa o itšetlehileng ka tekanyetso. Kalafo ea metadoxine ho tloha ka letsatsi la 4 ho isa ho la 8 ea hlokahala bakeng sa ho thibela phapang ea preadipocyte e bakoang ke MDI. Metadoxine e thibela ho fokotseha ha glutathione le keketseho ea tšenyo ea lipid peroxidation e bakoang ke ethanol le acetaldehyde liseleng tsa HepG2. Liseleng tsa hepatic stellate, Metadoxine e thibela keketseho ea collagen le secretion ea TNF-α e fokolisitsoeng e bakoang ke acetaldehyde. Kahoo, Metadoxine e ka ba molemo ho thibela tšenyo e hlahisoang matsatsing a pele a lefu la sebete sa tahi kaha e thibela ho se leka-lekane ha redox ea hepatocyte le ho thibela ho kenella ha TNF-α, e leng e 'ngoe ea liketsahalo tsa pele tsa tšenyo ea sebete.

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Selelekela

Metadoxin, e tsejoang ka lik'hemik'hale e le N,N-dimethylformamide, ke mokelikeli o se nang 'mala. Lintho tsa eona ke tse latelang:

Thepa ea 'mele: Metadoxine ke mokelikeli o se nang 'mala o monko o hlabang, o fetohang mocheso oa kamore, o tsoakana le metsi le lihlapolli tse tloaelehileng tsa tlhaho.

Thepa ea lik'hemik'hale: Metadoxine ke motsoako o fokotsang haholo o ka tšelisoang ke sodium hydroxide kapa sodium carbonate solutions ho etsa formamide le methanol.

Tšebeliso ea metaxacin:

Catalyst: Metadoxine e ka sebelisoa e le sejalo sa li-catalysts tsa tšepe, 'me e sebelisetsoa ho susumetsa karabelo ea sebopeho sa li-amine ho organic synthesis.

Li-solvents: Metadoxine e sebelisoa haholo joalo ka motsoako oa motsoako oa lintho tse phelang, joalo ka ho qhibiliha ha litšepe, li-polymers, le li-intermediate bakeng sa karabelo e matla.

Mokhoa oa ho itokisa: Tokiso ea metadoxine hangata e fumanoa ka karabelo ea formamidine le formic acid.

Tlhahisoleseding ka polokeho: Metaxacin ea teneha ebile ea senya, 'me e na le phello e halefisang letlalong, mahlo le lera la mucous. Tlhokomelo e lokela ho nkoa ho qoba ho kopana ka ho toba le letlalo le mahlo, 'me li-gloves tse sireletsang le likhalase li lokela ho apesoa ha ho hlokahala. Tlhokomelo e lokela ho lefshoa ho moea oa moea nakong ea tšebeliso ho qoba ho hema mouoane oa eona. Meltadoxine ke ntho e chang 'me e lokela ho behoa hole le malakabe a bulehileng le mehloli ea mocheso o phahameng.

E fetileng: L-Aspartic acid benzyl ester (CAS# 7362-93-8)

E 'ngoe: 1-Isopropoxy-1 1 2 2-tetrafluoroethane (CAS# 757-11-9)

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