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sehlahisoa

isosorbide dinitrate (CAS#87-33-2)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule C6H8N2O8
'Misa oa Molar 236.14
Botenya 1.7503 (khakanyo e fosahetseng)
Melting Point 700C
Boling Point 378.59°C (khakanyo e boima)
Phetoho e khethehileng(α) D20 +135° (alc)
Flash point 186.6°C
Ho qhibiliha ha Metsi 549.7mg/L(25 ºC)
Solubility Undiluted isosorbide dinitrate e qhibiliha hanyenyane haholo metsing, e qhibiliha haholo ka har'a acetone, e qhibiliha hanyenyane ka ethanol (96 lekholong). The solubility ea sehlahisoa hlapolotsoeng e itšetlehile ka diluent le mahloriso a eona.
Khatello ea Mouoane 3.19E-05mmHg ho 25°C
Ponahalo makhethe
Mmala Bosoeu ho isa ho bosoeu
Boemo ba polokelo -20°C Sehatsetsi
Refractive Index 1.5010 (khakanyo)
Thepa ea 'Mele le ea Lik'hemik'hale Phofo e tšoeu ea kristale. Ntho e qhibilihang ke 70 ° C, e qhibilihang ka chloroform, acetone, e qhibilihang hanyenyane ka ethanol, e qhibilihang ka metsing. Ha e na monko. Ho phatloha ho tlase ho feta nitroglycerin.
Sebelisa Coronary vasodilators bakeng sa phekolo ea angina pectoris

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Matšoao a Kotsi Xn - E Kotsi
Likhoutu tsa Kotsi R5 - Ho futhumatsa ho ka baka ho phatloha
R22 – E kotsi ha e kwetswe
Tlhaloso ea Tšireletseho 36 - Apara liaparo tse loketseng tsa tšireletso.
Li-ID tsa UN UN 2907
Khoutu ea HS 2932999000
Sehlopha sa Likotsi 4.1
Sehlopha sa ho paka II
Chefo LD50 molomo ka rat: 747mg/kg

 

Selelekela

Isosorbide dinitrate. Se latelang ke selelekela sa thepa, tšebeliso, mekhoa ea ho lokisa le tlhaiso-leseling ea polokeho ea isosorbide nitrate:

 

1. Tlhaho:

- Ponahalo: Isosorbide dinitrate hangata ke mokelikeli o se nang 'mala ho isa ho o mosehla o mosehla.

- Monko: E na le tatso e hlabang.

- Solubility: E qhibiliha ka metsing le ka har'a lihlapolli tsa tlhaho, joalo ka ethanol, ether, jj.

 

2. Tšebeliso:

- Isosorbide nitrate e sebelisoa haholo-holo ha ho etsoa liqhomane le phofo ea sethunya. E le ntho e matla e nang le naetrojene e ngata, e sebelisoa haholo libakeng tsa sesole le tsa baahi.

- Isosorbide nitrate e ka boela ea sebelisoa e le moemeli oa nitrification ho organic synthesis.

 

3. Mokhoa:

- Tokiso ea isosorbide nitrate hangata e fumanoa ka oxidation ea isosorbate (mohlala, isosorbide acetate). Moemeli oa oxidizing e ka ba likhahla tse phahameng tsa nitric acid kapa lead nitrate, joalo-joalo.

 

4. Litaba tsa Polokeho:

- Isosorbide nitrate ke ntho e phatlohang e kotsi haholo. E lokela ho bolokoa ka har'a setshelo se sa cheng, se sa phatloheng le se tiisitsoeng hantle, hole le mehloli ea mollo le mocheso.

- Mehato e nepahetseng ea ts'ireletso e tlameha ho nkoa ha u jara, u boloka, 'me u tšoara isosorbide dinitrate, ho kenyelletsa le ho roala mahlo a sireletsang mahlo, liatlana le mese, ho netefatsa moea o motle, le ho qoba ho hema kapa ho kopana.

- Ha u sebetsana le nitrate ea isosorbide, mekhoa e sebetsang ea ts'ireletso ea ts'ireletso e lokela ho lateloa 'me litokisetso tsa melao le melaoana li lokela ho lateloa.

 


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