Fmoc-O-trityl-L-serine (CAS# 111061-56-4)
E hlahisa Fmoc-O-trityl-L-serine (CAS # 111061-56-4), moaho oa premium bakeng sa peptide synthesis e etselitsoeng ho phahamisetsa lipatlisiso tsa hau le merero ea nts'etsopele ho ea holimo. Motsoako ona oa bohloeki bo phahameng o bohlokoa bakeng sa litsebi tsa k'hemistri le biochemist tse batlang ho theha li-peptide tse rarahaneng ka nepo le katleho.
Fmoc-O-trityl-L-serine ke mofuta o sirelelitsoeng oa serine ea amino acid, e nang le motsoako o ikhethang oa lihlopha tse sireletsang tsa Fmoc (9-fluorenylmethoxycarbonyl) le trityl (Tr). Leano lena la ts'ireletso e habeli ha le ntlafatse feela botsitso ba masala a serine nakong ea ho kopanya empa hape le lumella ts'ireletso e ikhethileng, e leng khetho e nepahetseng bakeng sa solid-phase peptide synthesis (SPPS). Sehlopha sa Fmoc se thusa ho tlosoa habonolo tlas'a maemo a bonolo, ha sehlopha sa trityl se fana ka tšireletso e eketsehileng khahlanong le maikutlo a sa batleheng.
Ka mokhoa oa molek'hule oa C27H29NO4 le boima ba molek'hule oa 433.53 g / mol, Fmoc-O-trityl-L-serine e khetholloa ka ho qhibiliha ha eona ho phahameng ho li-solvents tsa organic, e leng ho etsang hore e sebetsane le mefuta e mengata ea li-synthetic applications. Bohloeki ba eona bo ikhethang bo netefatsa hore lihlahisoa tsa hau tsa ho qetela tsa peptide ke tsa boleng bo holimo, ha li na litšila tse ka behang liphetho tsa lipatlisiso kotsing.
Hore na o ntse o etsa li-peptide tsa kalafo, o ithuta tšebelisano ea liprotheine, kapa o ntse o hlahloba batho ba seng ba ntse ba sebelisa lithethefatsi, Fmoc-O-trityl-L-serine ke khetho e tšepahalang bakeng sa litlhoko tsa hau tsa motsoako. Sehlahisoa sa rona se lekoa ka matla 'me se tla le litokomane tse felletseng ho tšehetsa boiteko ba hau ba lipatlisiso.
Notlolla bokhoni ba peptide synthesis ea hau ka Fmoc-O-trityl-L-serine. Eba le phapang eo li-reagents tsa boleng bo holimo li ka e etsang ka laboratoring ea hau. Odara hona joale 'me u nke mohato oa pele oa ho fihlela lipheo tsa hau tsa mahlale ka kholiseho!
