Fmoc-L-homophenylalanine (CAS# 132684-59-4)
Kotsi le Polokeho
| Matšoao a Kotsi | Xi - Ea halefisang |
| Likhoutu tsa Kotsi | 36/37/38 - Ho halefisa mahlo, tsamaiso ea ho hema le letlalo. |
| Tlhaloso ea Tšireletseho | S22 - U se ke ua hema lerole. S24/25 - Qoba ho kopana le letlalo le mahlo. S44 - S35 - Thepa ena le setshelo sa eona li tlameha ho lahloa ka tsela e sireletsehileng. S28 - Ka mor'a ho kopana le letlalo, hlatsoa hang-hang ka sesepa-suds e ngata. S7 - Boloka setshelo se koetsoe ka thata. S4 - Ipoloke hole le libaka tsa bolulo. |
| WGK Jeremane | 3 |
| Khoutu ea HS | 2924 29 70 |
| Sehlopha sa Likotsi | TS'OALANG |
Selelekela
2. Solubility: Ho qhibiliha ka har'a li-solvents tse kang dimethyl sulfoxide (DMSO) le ethyl acetate (EtOAc), e ke keng ea qhibiliha metsing.
3. foromo ea molek'hule: C32H29NO4.
4. boima ba molek'hule: 495,58.
Tšebeliso e kholo ea Fmoc-L-homophenylalanine ke sehlopha se sireletsang peptide synthesis. Fmoc ke khutsufatso ea furoyl le derivatives ea eona, e ka sireletsang sehlopha sa amino ka li-amino acid. Ha ho batloa ketane ea peptide, sehlopha sa amino se ka fumaneha bakeng sa karabelo ka ho tlosa sehlopha se sirelletsang sa Fmoc. Ka hona, Fmoc-L-homophenylalanine e phetha karolo ea bohlokoa ho lokiseng lithethefatsi tsa peptide le limolek'hule tse amanang le bioactive.
Mokhoa oa ho lokisa oa Fmoc-L-homophenylalanine o batla o rarahane mme o kenyelletsa karabelo ea mekhahlelo e mengata. Mokhoa o tloaelehileng oa ho itokisa ke oa ho sebelisana le Fmoc-protected phenylalanine le li-reagents tse ling, tse kang silver azide formate (AgNO2), e lateloa ke phekolo ea trifluoroacetic acid ho fana ka Fmoc-L-homophenylalanine.
Lintlha tse latelang tsa polokeho li lokela ho hlokomeloa ha u sebelisa Fmoc-L-homophenylalanine:
1. qoba ho kopana ka ho toba le letlalo, mahlo le lera la mucous, hobane e ka 'na ea halefisa' mele oa motho.
2. Ho boloka ho lokela ho qoba ho kopana le li-oxidants tse matla kapa li-acids tse matla ho thibela liketso tse kotsi.
3. Sebelisa lisebelisoa tse loketseng tsa ho itšireletsa tse kang liatlana, likhalase tse sireletsang le lijase tsa laboratori nakong ea ha u li sebelisa le ho li tšoara.
4. Mesebetsi eohle e lokela ho etsoa tlas'a maemo a laboratori a nang le moea o motle.
Ka bokhuts'oane, Fmoc-L-homophenylalanine ke sehlopha se sireletsang amino acid se atisang ho sebelisoa ha ho etsoa peptide synthesis 'me se na le mefuta e mengata ea ts'ebeliso. Ha u sebelisa le ho sebetsana le motsoako, hoa hlokahala ho ela hloko ho tšoara le ho boloka ka mokhoa o sireletsehileng.
