fmoc-L-4-hydroxyproline (CAS# 88050-17-3)

Selelekela

Fmoc-L-hydroxyproline (Fmoc-Hyp-OH) ke motsoako oa amino acid e nang le thepa le ts'ebeliso e latelang:

Boleng:

- Ponahalo: phofo e tšoeu kapa e tšoeu ea kristale

- Solubility: E qhibiliha ka har'a lihlapolli tsa tlhaho tse kang DMF, DMSO le methanol

- boleng ba pKa: 2.76

Sebelisa:

- Fmoc-Hyp-OH e sebelisoa haholo bakeng sa peptide synthesis le peptide synthesis ho solid-phase synthesis

- E sebetsa e le karolo ea sehlopha se sireletsang ho sireletsa lihlopha tse sebetsang tsa ketane ea mahlakoreng ea li-amino acid nakong ea motsoako o tiileng ho qoba karabelo e sa lebelloang le ho boloka khetho.

Mokhoa:

Fmoc-Hyp-OH e ka lokisoa ka ho arabela Fmoc-amino acid ka L-hydroxyproline ka har'a motsoako o loketseng. Maemo a karabelo hangata a kenyelletsa mocheso o loketseng oa karabelo le sesebelisoa se loketseng, joalo ka N,N-dimethylpyrrolidone (DMAP). Sehlahisoa se hlahisoang se hloekisoa ka mehato e kang ea pula, ho hlatsoa le ho omisa.

Lintlha tsa Tšireletseho:

- FMOC-HYP-OH ke motsoako oa lintho tse phelang 'me o lokela ho sebetsoa ho latela melaoana ea ts'ireletso ea laboratori.

- Lerōle le ka hema 'me la kopana le letlalo, kahoo ho lokela ho nkoa tlhokomelo ho qoba ho hema ka ho toba kapa ho kopana.

- Nakong ea ts'ebetso, lisebelisoa tsa ts'ireletso tse nepahetseng joalo ka liatlana tsa laboratori, ts'ireletso ea mahlo, liaparo tse sireletsang, joalo-joalo li lokela ho apesoa.

- E lokela ho bolokoa e tiisitsoe ka thata sebakeng se omileng, se phodileng, hole le mollo le lintho tse tukang.