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sehlahisoa

FMOC-Glycine (CAS# 29022-11-5)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule C17H15NO4
'Misa oa Molar 297.31
Botenya 1.1671 (khakanyo e fosahetseng)
Melting Point 174-175°C(lebone)
Boling Point 438.82°C (khakanyo e boima)
Flash point 283.8°C
Solubility hoo e batlang e le pepeneneng ho Methanol
Khatello ea Mouoane 9.69E-13mmHg ho 25°C
Ponahalo Likristale tse tšoeu ho isa ho tse mosehla o khanyang
Mmala Bosoeu
BRN 2163967
pKa 3.89±0.10(E boletsoeng esale pele)
Boemo ba polokelo 2-8°C
Refractive Index 1.4500 (khakanyo)
MDL MFCD00037140
Sebelisa E sebelisoa bakeng sa li-reagents tsa biochemical, peptide synthesis.

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Matšoao a Kotsi Xi - Ea halefisang
Likhoutu tsa Kotsi 36/37/38 - Ho halefisa mahlo, tsamaiso ea ho hema le letlalo.
Tlhaloso ea Tšireletseho S24/25 - Qoba ho kopana le letlalo le mahlo.
S36 - Apara liaparo tse loketseng tsa tšireletso.
S26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka.
WGK Jeremane 3
Khoutu ea HS 29242995

 

Selelekela

N-Fmoc-glycine ke motsoako oa bohlokoa oa amino acid, 'me lebitso la eona la lik'hemik'hale ke N-(9H-fluoroeidone-2-oxo) -glycine. Se latelang ke selelekela sa thepa, tšebeliso, mekhoa ea ho lokisa le tlhaiso-leseling ea polokeho ea N-Fmoc-glycine:

 

Boleng:

- Ponahalo: Bosoeu kapa bosoeu bo tiileng

- Solubility: E qhibiliha ka har'a metsoako ea lintho tse phelang tse kang dimethyl sulfoxide (DMSO) le methylene chloride, e qhibilihang hanyenyane joala, e batlang e sa qhibilihe ka metsing.

 

Sebelisa:

N-Fmoc-glycine e sebelisoa haholo-holo bakeng sa peptide synthesis ka solid-phase synthesis (SPPS). E le amino acid e sirelelitsoeng, e eketsoa ketane ea polypeptide ka motsoako o tiileng, 'me qetellong sepheo sa peptide se fumanoa ka karabelo ea lihlopha tse thibelang tšireletso.

 

Mokhoa:

Tokisetso ea N-Fmoc-glycine hangata e etsoa ke karabelo ea lik'hemik'hale. Glycine e sebetsa ka N-fluorophenyl methyl alcohol le base (mohlala, triethylamine) ho hlahisa N-fluorophenylmethyl-glycine hydrochloride. Joale, hydrochloric acid e tlosoa ke mofuta o mong oa deacidifier, joalo ka dimethyl sulfoxide kapa sec-butanol, ho fana ka N-Fmoc-glycine.

 

Lintlha tsa Tšireletseho:

N-Fmoc-Glycine e batla e bolokehile tlas'a maemo a tloaelehileng a ts'ebetso

- Ka kopo, roala lisebelisoa tse nepahetseng tsa ts'ireletso joalo ka liatlana tsa lab le ts'ireletso ea mahlo.

- Qoba ho hema kapa ho kopana le letlalo le mahlo.

- Latela melaoana eohle e amehang ea polokeho le liprothokholo tsa laboratori ha u boloka le ho sebetsana.

- Ela hloko ho bokellana ha motlakase le motlakase o tsitsitseng nakong ea ts'ebetso ho thibela kotsi ea mollo le ho phatloha.

- Ho lahla litšila ka mokhoa o nepahetseng ho latela litlhoko tsa ho boloka le ho lahla thepa.

 


  • E fetileng:
  • E 'ngoe:

  • Ngola molaetsa wa hao mona mme o re romele wona