FMOC-Glycine (CAS# 29022-11-5)
Matšoao a Kotsi | Xi - Ea halefisang |
Likhoutu tsa Kotsi | 36/37/38 - Ho halefisa mahlo, tsamaiso ea ho hema le letlalo. |
Tlhaloso ea Tšireletseho | S24/25 - Qoba ho kopana le letlalo le mahlo. S36 - Apara liaparo tse loketseng tsa tšireletso. S26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka. |
WGK Jeremane | 3 |
Khoutu ea HS | 29242995 |
Selelekela
N-Fmoc-glycine ke motsoako oa bohlokoa oa amino acid, 'me lebitso la eona la lik'hemik'hale ke N-(9H-fluoroeidone-2-oxo) -glycine. Se latelang ke selelekela sa thepa, tšebeliso, mekhoa ea ho lokisa le tlhaiso-leseling ea polokeho ea N-Fmoc-glycine:
Boleng:
- Ponahalo: Bosoeu kapa bosoeu bo tiileng
- Solubility: E qhibiliha ka har'a metsoako ea lintho tse phelang tse kang dimethyl sulfoxide (DMSO) le methylene chloride, e qhibilihang hanyenyane joala, e batlang e sa qhibilihe ka metsing.
Sebelisa:
N-Fmoc-glycine e sebelisoa haholo-holo bakeng sa peptide synthesis ka solid-phase synthesis (SPPS). E le amino acid e sirelelitsoeng, e eketsoa ketane ea polypeptide ka motsoako o tiileng, 'me qetellong sepheo sa peptide se fumanoa ka karabelo ea lihlopha tse thibelang tšireletso.
Mokhoa:
Tokisetso ea N-Fmoc-glycine hangata e etsoa ke karabelo ea lik'hemik'hale. Glycine e sebetsa ka N-fluorophenyl methyl alcohol le base (mohlala, triethylamine) ho hlahisa N-fluorophenylmethyl-glycine hydrochloride. Joale, hydrochloric acid e tlosoa ke mofuta o mong oa deacidifier, joalo ka dimethyl sulfoxide kapa sec-butanol, ho fana ka N-Fmoc-glycine.
Lintlha tsa Tšireletseho:
N-Fmoc-Glycine e batla e bolokehile tlas'a maemo a tloaelehileng a ts'ebetso
- Ka kopo, roala lisebelisoa tse nepahetseng tsa ts'ireletso joalo ka liatlana tsa lab le ts'ireletso ea mahlo.
- Qoba ho hema kapa ho kopana le letlalo le mahlo.
- Latela melaoana eohle e amehang ea polokeho le liprothokholo tsa laboratori ha u boloka le ho sebetsana.
- Ela hloko ho bokellana ha motlakase le motlakase o tsitsitseng nakong ea ts'ebetso ho thibela kotsi ea mollo le ho phatloha.
- Ho lahla litšila ka mokhoa o nepahetseng ho latela litlhoko tsa ho boloka le ho lahla thepa.