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Fmoc-D-Trp(Boc)-OH (CAS# 163619-04-3)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule C31H30N2O6
'Misa oa Molar 526.58
Botenya 1.28±0.1 g/cm3(E boletsoeng esale pele)
Melting Point 86 - 92 ℃ (D℃omposes)
Ponahalo Phofo ea kristale e tšoeu ho isa bosoeu
BRN 7062970
pKa 3.71±0.10(E boletsoeng esale pele)
Boemo ba polokelo 2-8°C
Refractive Index 1.632
MDL MFCD00153367
Thuto ea in vitro Li-ADC li entsoe ka lesole la 'mele leo ho lona ho kentsoeng cytotoxin ea ADC ka sehokelo sa ADC.

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Kotsi le Polokeho

Tlhaloso ea Tšireletseho S22 - U se ke ua hema lerole.
S24/25 - Qoba ho kopana le letlalo le mahlo.
WGK Jeremane 3
LIKHOUTU FLUKA BRAND F 10
Khoutu ea HS 29339900

Fmoc-D-Trp(Boc)-OH (CAS# 163619-04-3) selelekela

N-alpha-fluorene methoxycarbonyl-N-in-tert-butoxycarbonyl-D-tryptophan ke motsoako oa amino acid, o tsejoang hape e le Fmoc-Trp(Boc) -OH. Mona ke lintlha tse ling mabapi le thepa ea eona, ts'ebeliso, mekhoa ea tlhahiso le polokeho:

Boleng:
- Ponahalo: E tiileng ka kristale e tšoeu
- Solubility: E qhibiliha ka har'a lihlapolli tsa lintho tse phelang tse kang methylene chloride le dimethyl sulfoxide, e ke keng ea qhibiliha ka metsing.

Sebelisa:
- Fmoc-Trp (Boc) -OH e sebelisoa haholo tšimong ea peptide synthesis 'me e sebelisoa e le sehlopha se sireletsang ho manyolo a tlhaho.

Mokhoa:
- Tokiso ea Fmoc-Trp(Boc) -OH hangata e na le mehato e 'meli. Lihlopha tsa amino tsa liketane tsa mahlakoreng a tryptophan li sirelelitsoe ka sehlopha se sireletsang, hangata ka dihydrazine spinachlate (Fmoc). Ea bobeli, tert-butylhydroxymethylic acid acetal (Boc) e sebelisetsoa ho sireletsa sehlopha sa hydroxyl sa tryptophan.

Lintlha tsa Tšireletseho:
- Fmoc-TRP (Boc) -OH e ka 'na ea halefisa letlalo, mahlo, le tsamaiso ea phefumoloho,' me e lokela ho sebelisoa ka thepa e nepahetseng ea tšireletso ho netefatsa hore ho na le moea o lekaneng oa moea.
- Tlhokomelo e lokela ho nkoa ho qoba ho hema, ho metsa, kapa ho kopana ha u sebelisa kapa u tšoara Fmoc-Trp(Boc) -OH.


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