FMOC-D-NVA-OH (CAS# 144701-24-6)

FMOC-D-NVA-OH (CAS# 144701-24-6) ke sehlopha se sireletsang amino acid se atisang ho sebelisoa ha ho etsoa li-peptide le liprotheine. E latelang ke tlhaloso ea mofuta, tšebeliso, tlhahiso le tlhahisoleseling ea polokeho ea fmoc-D-norvaline:

Tlhaho:
fmoc-D-norvaline ke ntho e tiileng e tšoeu, hangata e le phofo. E qhibiliha hantle linthong tse qhalang tse kang N,N-dimethylformamide (DMF) kapa dichloromethane (DCM). Motsoako o na le botsitso bo phahameng ba mocheso 'me o ka tsitsa ho li-solvents tse tloaelehileng.

Sebelisa:
fmoc-D-norvaline e sebelisoa haholo-holo e le sehlopha se sireletsang amino acid ha ho etsoa li-peptide le liprotheine. E ka amahanngoa le li-amino acid tse ling ka motsoako o tiileng-phase synthesis, e ka sireletsang ka nakoana li-amino acid tse ling nakong ea motsoako. Hang ha peptide chain synthesis e felile, sehlopha se sireletsang Fmoc se ka tlosoa ka kalafo ea motheo.

Mokhoa:
fmoc-D-norvaline hangata e lokisoa ke metsoako ea lik'hemik'hale, 'me D-norvaline e le eona ntho ea ho qala. Tšimoloho e kenyelletsa ho sebetsana le norvaline le sehlopha se sireletsang Fmoc ho hlahisa sehlopha sa Fmoc ka karabelo e ncha. Qetellong fumana fmoc-D-norvaline.

Lintlha tsa Tšireletseho:
fmoc-D-norvaline e batla e bolokehile tlas'a maemo a tloaelehileng a ts'ebetso ea laboratori, mekhoa e meng ea mantlha ea ts'ebetso e ntse e hloka ho lateloa. Qoba ho kopana le letlalo le mahlo nakong ea tšebeliso, 'me u netefatse hore u sebetsa sebakeng se nang le moea o motle. Lisebelisoa tse loketseng tsa ho itšireletsa, tse kang liatlana tsa lab le likhalase tsa tšireletso, li lokela ho roaloa ha u tšoara motsoako. Ho feta moo, litšila li lokela ho lahloa ka nepo le ho lahloa ho latela melaoana e amehang. Haeba kotsi leha e le efe e sa lebelloang e etsahala, mehato e tsamaisanang ea thuso ea pele e lokela ho nkoa hang-hang. Tšebelisong le polokelong ea fmoc-D-norvaline, melaoana e nepahetseng ea polokeho ea lik'hemik'hale e lokela ho hlokomeloa.