Fmoc-D-Cyclohexyl glycine (CAS# 198543-96-3)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule	C23H25NO4
'Misa oa Molar	379.45
Botenya	1.238
Melting Point	161-187 ℃
Boling Point	602.9±38.0 °C(E boletsoeng esale pele)
Ponahalo	Phofo e tšoeu ho isa ho e tšoeu
pKa	3.89±0.10(E boletsoeng esale pele)
Boemo ba polokelo	E tiisitsoe ka ho omme, Mocheso oa Kamore

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Kotsi le Polokeho

Sehlopha sa Likotsi

TS'OALANG

Fmoc-D-Cyclohexyl glycine (CAS# 198543-96-3) Boitsebiso

Sebelisa

Fluorene methoxycarbonyl D-cyclohexylglycine ke motsoako o tloaelehileng oa meriana le lik'hemik'hale, fluorenyl chloride (FMOC-Cl) ke chloroformate. E sebelisoa ho theha fluorene methoxycarbonyl (sehlopha sa FMOC) ho fluorene methoxycarbonyl carbamate FMOC carbamate, e leng sehlopha se tloaelehileng se sireletsang amino.

Tokisetso

Tšimoloho ea fluorene methoxycarbonyl D-cyclohexylglycine e tlalehiloe libukeng. Ho sebelisa cyclohexyl bromide e le thepa e tala, ka pel'a sodium alkoxide, e etsa hore alkylation reaction e be le diethyl malonate, ebe e hydrolyzes, acidifies, le decarboxylates ho fumana cyclohexyl acetic acid; ea ho qetela e ntan'o ba brominated le ammonolysis DL-Cyclohexylglycine; Qetellong, karabelo ea acylation e hlaha boteng ba fluorene methoxycarbonyl chloride ho fumana fluorene methoxycarbonyl D-cyclohexylglycine [1]. Mokhoa oa ho etsa synthesis ke o latelang:

E fetileng: AC-TYR-NH2 (CAS# 1948-71-6)

E 'ngoe: 2-Amino-4-bromobenzoic acid (CAS# 20776-50-5)

Ngola molaetsa wa hao mona mme o re romele wona