Fmoc-2-Amino-2-methylpropionic acid (CAS# 94744-50-0)
| Tlhaloso ea Tšireletseho | S22 - U se ke ua hema lerole. S24/25 - Qoba ho kopana le letlalo le mahlo. |
| WGK Jeremane | 3 |
| LIKHOUTU FLUKA BRAND F | 10-21 |
| Khoutu ea HS | 29242990 |
| Sehlopha sa Likotsi | TS'OALANG |
Selelekela
Fmoc-2-aminoisobutyric acid, eo hape e tsejoang e le Fmoc-Aib, ke motsoako oa manyolo. Se latelang ke selelekela se qaqileng ho tse ling tsa thepa, ts'ebeliso, mekhoa ea ho lokisa le tlhaiso-leseling ea polokeho ea Fmoc-2-aminoisobutyric acid:
Boleng:
Fmoc-2-aminoisobutyric acid ke kristale e tšoeu e tiileng e nang le monko o ikhethang. E tsitsitse mocheso oa kamore 'me ha e qhibilihe ka metsing, empa e qhibiliha ka har'a metsoako ea tlhaho e kang methanol le methylene chloride.
Sebelisa:
Fmoc-2-aminoisobutyric acid ke sehlopha sa ts'ireletso se sebelisoang hangata ho organic synthesis. E ka sebelisoa e le sehlopha bakeng sa tšireletso ea nakoana ea lihlopha tsa amino ka li-polypeptide tsa maiketsetso le liprotheine ho li thibela ho itšoara ka mahlakoreng ka liketso tsa lik'hemik'hale.
Mokhoa:
Mokhoa oa ho itokisa oa FMOC-2-aminoisobutyric acid ka kakaretso ke ka motsoako oa lik'hemik'hale. Hangata sena se etsoa ke karabelo ea 2-aminoisobutyric acid le Fmoc-OSu (Fmoc-N-hydroxysuccinimidyl) kapa Fmoc-OXy (Fmoc-N-hydroxysuccinimidate). Karabelo hangata e etsoa ka mocheso oa kamore mme e hloekisoa ka ho ntšoa ha solvent le crystallization.
Lintlha tsa Tšireletseho:
FMOC-2-aminoisobutyric acid hangata e batla e bolokehile tlas'a maemo a tloaelehileng a tšebeliso. Joalo ka motsoako oa manyolo, e ka baka likotsi tse itseng bophelong ba motho. Tlhokomelo e lokela ho nkoa ho qoba ho hema phofo kapa tharollo ha u ntse u qoba ho kopana le letlalo le mahlo. Liatlana tse sireletsang, likhalase le limaske li lokela ho roaloa ha ho hlokahala. Haeba u kopana le letlalo kapa mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle ngaka. E lokela ho bolokoa sebakeng se omeletseng, se phodileng, hole le mollo le li-oxidants.
