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Doxofylline (CAS# 69975-86-6)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule C11H14N4O4
'Misa oa Molar 266.25
Botenya 1.2896 (khakanyo e fosahetseng)
Melting Point 144-146°C
Boling Point 409.46°C (khakanyo e boima)
Flash point 259.3°C
Ho qhibiliha ha Metsi E qhibilihang
Solubility E qhibiliha ka metsing, acetone, ethyl acetate, benzene, chloroform, dioxane, hot methanol kapa ethanol e chesang, e batlang e sa qhibilihe ho ether kapa petroleum ether.
Khatello ea Mouoane 2.49E-10mmHg ho 25°C
Ponahalo Crystallization
Mmala Bosoeu ho isa ho bosoeu
Merck 14,3438
pKa 0.42±0.70(E boletsoeng esale pele)
Boemo ba polokelo tlas'a khase ea inert (naetrojene kapa Argon) ho 2-8°C
Refractive Index 1.6000 (khakanyo)
MDL MFCD00865218

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Kotsi le Polokeho

Matšoao a Kotsi Xi - Ea halefisang
Likhoutu tsa Kotsi 36/37/38 - Ho halefisa mahlo, tsamaiso ea ho hema le letlalo.
Tlhaloso ea Tšireletseho S26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka.
S36/37 - Apara liaparo tse loketseng tsa tšireletso le liatlana.
RTECS XH5135000
Khoutu ea HS 29399990
Chefo LD50 ka litoeba (mg / kg): 841 ka molomo; 215.6 iv; ka likhoto: 1022.4 ka molomo, 445 ip (Franzone)

 

Doxofylline (CAS# 69975-86-6) Ho hlahisa

Ho hlahisa Doxofylline (CAS# 69975-86-6) - bronchodilator ea phetoho e etselitsoeng ho ntlafatsa bophelo bo botle ba ho hema le ho ntlafatsa bophelo ba batho ba nang le maemo a sa foleng a phefumoloho. Joalo ka setho sa sehlopha sa xanthine sa meriana, Doxofylline e fana ka mokhoa o ikhethileng oa ts'ebetso o e khethollang ho li-bronchodilator tsa setso, e e etsa tlatsetso ea bohlokoa ho setsi sa kalafo sa asthma le taolo ea lefu le sa foleng la matšoafo (COPD).

Doxofylline e sebetsa ka ho khatholla mesifa e boreleli ea moea, e lebisang ho phallo e ntle ea moea le ho fokotsa khatello ea maikutlo. Ketso ea eona e habeli ha e atolose liphaseje tsa bronchial feela empa hape e na le thepa e khahlanong le ho ruruha, e sebetsanang le ho ruruha ho teng hoo hangata ho mpefatsang maemo a phefumoloho. Sena se etsa hore Doxofylline e be khetho e sebetsang ho bakuli ba batlang ho imoloha ho hema, ho hema ka thata le matšoao a mang a amanang le asthma le COPD.

E 'ngoe ea likarolo tse hlahelletseng tsa Doxofylline ke boemo ba eona bo botle ba polokeho. Ho fapana le li-bronchodilator tse ling, ha ho bonolo ho baka litla-morao tse kang tachycardia kapa tšitiso ea mala, e leng se etsang hore e loketse tšebeliso ea nako e telele. Ntle le moo, Doxofylline e fumaneha ka mefuta e fapaneng, ho kenyeletsoa matlapa le li-inhalers, e fanang ka maemo le bonolo ho bakuli ho laola maemo a bona.

Ka katleho ea eona e netefalitsoeng le polokeho, Doxofylline e se e fetoha khetho e ratoang har'a litsebi tsa bophelo bo botle. E matlafatsa bakuli ho laola bophelo ba bona ba phefumoloho, e ba lumella ho etsa mesebetsi ea letsatsi le letsatsi ka kholiseho le boiketlo.

E-ba le phapang pakeng tsa Doxofylline - molekane ea tšeptjoang ntoeng khahlanong le mafu a ho hema. Ikopanye le mofani oa tlhokomelo ea bophelo kajeno ho ithuta haholoanyane ka hore na Doxofylline e ka u thusa ho hema ha bonolo le ho phela betere.


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