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D-Glutamine (CAS # 5959-95-5) Setšoantšo se hlahang
  • D-Glutamine (CAS# 5959-95-5) 1

D-Glutamine (CAS# 5959-95-5)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule C5 H10 N2 O3
'Misa oa Molar 146.14
Botenya 1.3394 (khakanyo e fosahetseng)
Melting Point 184-185 °C
Boling Point 265.74°C (khakanyo e boima)
Phetoho e khethehileng(α) -32 º (589nm, c=10, N HCl)
Ho qhibiliha ha Metsi 42.53g/L(mocheso ha o boleloe)
Solubility E qhibiliha ka metsing (9 mg/ml ho 25 °C), DMSO (<1 mg/ml ho 25 °C), le ethanol (<1 mg/m
Ponahalo Phofo e tšoeu ea kristale
Mmala Bosoeu
BRN 1723796
pKa 2.27±0.10(E boletsoeng esale pele)
Boemo ba polokelo Lula sebakeng se lefifi, sepakapaka se se nang moea, mocheso oa kamore
Refractive Index -33 ° (C=5, 5mol/LH
MDL MFCD00065607
Thepa ea 'Mele le ea Lik'hemik'hale Sebaka sa ho qhibiliha: 185
Thuto ea in vitro Glutamine ke amino acid ea bohlokoa tsamaisong ea methapo e bohareng (CNS), e bapala karolo ea bohlokoa ho glutamate / GABA-Glutamine cycle (GGC). Ho GGC, Glutamine e fetisoa ho tloha ho astrocyte ho ea ho li-neuron, moo e tla tlatsa matamo a thibelang le a thabisang a methapo ea kutlo. D-Glutamine e 'nile ea sebelisoa ho ithuta karolo ea eona ea ho fana ka tšireletso khahlanong le tšitiso e bakoang ke acetaldehyde ea ts'ebetso ea thibelo ho Caco-2 cell monolayer. Karolo ea L-Glutamine ts'ireletsong ea epithelium ea mala ho tsoa ho tšitiso e bakoang ke acetaldehyde ea ts'ebetso ea thibelo e hlahlojoa ho Caco-2 cell monolayer. L-Glutamine e fokolitse ho fokotseha ho bakoang ke acetaldehyde ho hanyetsa motlakase oa transepithelilal le ho eketseha ha ho khoneha ho inulin le lipopolysaccharide ka mokhoa o itšetlehileng ka nako le tekanyo; D-Glutamine, L-aspargine, L-arginine, L-lysine, kapa L-alanine ha e hlahise tšireletso e kholo. D-Glutamine e boetse e hloleha ho susumetsa ho fokotseha ho bakoang ke acetaldehyde ho TER le ho eketseha ha inulin flux. D-Glutamine kapa glutaminase inhibitor ka bobona ha ea ka ea susumetsa TER kapa inulin flux taolong kapa acetaldehyde-treated cell monolayers. Ho haella ha phello ea D-Glutamine tšireletsong ea acetaldehyde ho bontša hore tšireletso ea L-Glutamine-mediated ke stereospecific.

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Motsoako oo e seng oa tlhaho oa glutamine ha e le hantle ha o qhibilihe ka har'a methanol, ethanol, ether le benzene.

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