BOC-N-Methyl-L-alanine (CAS# 16948-16-6)
Kotsi le Polokeho
| Tlhaloso ea Tšireletseho | 24/25 - Qoba ho kopana le letlalo le mahlo. |
| WGK Jeremane | 3 |
| Khoutu ea HS | 2924 19 00 |
| Sehlopha sa Likotsi | TS'OALANG |
BOC-N-Methyl-L-alanine (CAS# 16948-16-6) Boitsebiso
| kopo | BOC-N-methyl-L-alanine e ka sebelisoa eseng feela bakeng sa motsoako oa protheine, empa hape e le se matlafatsang tatso, se sireletsang le se bolokang lijo tšimong ea lijo, joalo ka lisebelisoa tse tala tsa meriana lefapheng la bongaka le motsoako o bonolo oa surfactant tšimong ea letsatsi le letsatsi ea lik'hemik'hale. |
| tokisetso | Tetrahydrofuran (80 mL) tharollo ea 1-boc-alanine (5g, 26.4 mmol) e kentsoe, phofo e ntle KOH (10.4g, 187 mmol) e ile ya eketswa ho 0 ℃, mme ebe tetrabutylammonium bisulfate (0.5g, 10% ka boima ba 'mele) e eketsoa. Ebe, dimethyl sulfate (10 mL, 105 mmol) e ile ea eketsoa ka tlase ho feta metsotso e 15. Kopanya metsotso e meng e 30 ebe u eketsa metsi (50 ml). Kamora ho hlohlelletsa mocheso oa kamore bakeng sa lihora tse 5, 20% ea ammonium hydroxide aqueous solution (20 ml) e ile ea eketsoa. Fokotsa karabelo ka ether (100 mL), arola lera la metsi, 'me u ntše lesela la manyolo ka tharollo ea metsi a NaHCO3 e tletseng metsi (2 × 40 mL). Lera le tsoakiloeng la metsi le entsoe asiti ka 1M KHSO4 ho pH 1 mme e ntšitsoe ka ethyl acetate (2×200 mL). Likarolo tsa manyolo li kopantsoe, li omisitsoe (Na2SO4), li tlhotliloeng ebile li tsepamisitsoe. Sehlahisoa se hlahisoang se ile sa tsejoa e le BOC-N-methyl-L-alanine. Botoro, tlhahiso ea 4.3g, 80%. |
Ngola molaetsa wa hao mona mme o re romele wona
