Boc-L-Tyrosine methyl ester (CAS# 4326-36-7)

Selelekela

N-Boc-L-Tyrosine Methyl Ester ke motsoako oa lik'hemik'hale oo lebitso la oona la lik'hemik'hale e leng N-tert-butoxycarbonyl-L-tyrosine methyl ester. Lintho tsa eona ke tse latelang:

1. Ponahalo: bosoeu ho isa ho bohlooho bo tiileng ba kristale;

5. Ho qhibiliha: ho qhibiliha ka har'a li-solvents tse kang ethanol le dimethylformamide (DMF), tse sa tsitsang metsing.

N-Boc-L-tyrosine methyl ester e atisa ho sebelisoa ho organic synthesis ho sireletsa amino acid ha ho etsoa metsoako ea polypeptide. Hangata e sebelisoa e le sehlopha se sireletsang sa L-tyrosine ho thibela liketso tse sa khetheheng karabelong hore li se ke tsa etsahala. Hang ha karabelo e phethiloe, sehlopha se sireletsang se ka tlosoa tlas'a maemo a loketseng ho fumana sehlahisoa se nepahetseng sa sepheo.

Mokhoa oa ho lokisa oa N-Boc-L-tyrosine methyl ester hangata o kenyelletsa mehato e latelang:

1. Hlakola L-tyrosine ka dimethylformamide (DMF);

2. Eketsa sodium carbonate ho fokotsa sehlopha sa carboxyl sa tyrosine;

3. Methanol le methyl carbonate (MeOCOCl) li kenngoa motsoako oa karabelo ho hlahisa N-Boc-L-tyrosine methyl ester. Hangata karabelo e etsoa ka mocheso o tlase, 'me ho sebelisoa ho feteletseng ha methyl carbonate ho netefatsa hore karabelo e tsoela pele.

N-Boc-L-tyrosine methyl ester e batla e tsitsitse, empa e ntse e hloka ho sebetsoa ka hloko. Lintlha tse latelang ke tse akaretsang tsa polokeho:

1. Qoba ho kopana le letlalo le mahlo: Li-gloves tse sireletsang le likhalase tse loketseng li lokela ho apesoa ho qoba ho kopana ka ho toba le motsoako;

2. Qoba ho hema: Ho lokela ho netefatsoe hore ho na le moea o motle sebakeng sa mosebetsi ho thibela ho hema ha likhase tse kopantsoeng;

3. Polokelo: E lokela ho bolokoa sebakeng se pholileng, se omileng ’me u qobe ho kopana le oksijene, liasiti tse matla, kapa litšiea tse matla.

Ka kakaretso, N-Boc-L-tyrosine methyl ester ke karolo ea bohlokoa lipakeng tsa organic synthesis mme e bapala karolo ea bohlokoa ho qaleng ha metsoako ea peptide. Tlhokomelo e lokela ho nkoa bakeng sa ts'ebetso e sireletsehileng ha e sebelisoa le ha e tšoaroa.