Boc-L-aspartic acid 1-benzyl ester (CAS# 30925-18-9)

Selelekela

Boc-Asp-OBzl(Boc-Asp-OBzl) ke motsoako o nang le thepa e latelang:

1. Ponahalo: E tiileng ka kristale e tšoeu.

2. Foromo ea molek'hule: C24H27N3O7.

3. Boima ba molek'hule: 469.49g / mol.

4. Sebaka se qhibilihang: hoo e ka bang 130-134 ° C.

Boc-Asp-OBzl e sebelisoa haholo ho biochemistry le synthetic organic chemistry, hangata e sebelisoa ha ho etsoa li-peptide, liprotheine le lithethefatsi, ka ts'ebeliso e latelang:

1. Peptide synthesis: Joaloka karolo ea sehlopha se sireletsang (Boc sireletsa sehlopha), sehlopha sa amino ka aspartic acid amino acid e ka sireletsoa.

2. Patlisiso ea lithethefatsi: bakeng sa ho qaptjoa ha lithethefatsi tsa peptide tse nang le ts'ebetso ea anti-inflammatory, anti-tumor le immune regulation.

3. Karabelo ea Enzyme: Boc-Asp-OBzl e ka sebelisoa bakeng sa enzyme catalyzed reaction substrate.

Mokhoa oa ho lokisa Boc-Asp-OBzl ke o latelang:

Aspartic acid le benzoyl chloride li entsoe esterified ho etsa tert-butoxycarbonyl-aspartic acid benzyl ester (Boc-Asp-OMe), eo ka mor'a moo e arabelang ka sodium hexoxide ho fumana mahareng ka sebopeho sa N-hexanoate. Qetellong, e ba le karabelo ea benzoylation ho hlahisa Boc-Asp-OBzl.

Ela hloko lintlha tse latelang tsa polokeho ha u sebelisa Boc-Asp-OBzl:

1. Motsoako ona o ka baka ho teneha le ho hanana le 'mele oa motho,' me ho kopana ka ho toba le letlalo le mahlo ho lokela ho qojoa.

2. Mehato e loketseng ea ho itšireletsa e lokela ho nkoa nakong ea ts'ebetso, e kang ho roala liatlana le likhalase.

3. Boloka e omme 'me e tiisitsoe nakong ea polokelo, 'me u lule hole le mollo le oxidant.

4. Ha u sebelisa le ho sebetsana le Boc-Asp-OBzl, ka kopo latela mekhoa e nepahetseng ea ts'ebetso ea laboratori le ts'ebetso e sireletsehileng.

Ka kopo elelloa hore ha u sebelisa Boc-Asp-OBzl kapa lik'hemik'hale life kapa life, u tlameha ho latela ka tieo litataiso tse ts'oanang tsa ts'ireletso, 'me u etse ts'ireletso ea hau le tlhahlobo ea kotsi ho latela maemo a nnete.