BOC-GLY-GLY-GLY-OH(CAS# 28320-73-2)

Selelekela

Tert-Butoxycarbonylglycyl glycylglycine (Boc-Gly-Gly-Gly-OH) ke motsoako oa tlhaho o nang le litšobotsi tse latelang:

Tlhaho:

-Ponahalo: hangata kristale e tšoeu kapa phofo ea crystalline

- Foromo ea molek'hule: C17H30N4O7

- Boima ba molek'hule: 402.44g / mol

- Sebaka sa ho qhibiliha: hoo e ka bang 130-132 ° C

-Solubility: E qhibiliha ka har'a li-solvents tse kang dimethylformamide (DMF), dichloromethane, chloroform, joalo-joalo, e ke keng ea qhibiliha ka metsing.

Sebelisa:

Boc-Gly-Gly-Gly-OH hangata e sebelisoa ho organic synthesis, haholo-holo e le lihlopha tse sireletsang kapa lihlopha. E ka sebelisoa e le sehlopha se sireletsang sa li-amino acid ho thibela mekhoa e sa tloaelehang, 'me e atisa ho sebelisoa ka mokhoa o tiileng oa ho kopanya, peptide synthesis le synthesis ea lithethefatsi.

Mokhoa:

Mokhoa o tloaelehileng oa ho lokisa Boc-Gly-Gly-Gly-OH ke ho hlahisa sehlopha sa tšireletso sa tert-butoxycarbonyl ho sehlopha sa carboxyl sa glycine. Mehato e khethehileng e kenyelletsa:

1. Glycine e itšoara ka motsoako oa sodium nitrite le sulfuric acid ho fumana tert-butoxycarbonyl glycinate.

2. Sehlopha se sireletsang Ester se tlosoa ke karabelo ea hydrolysis ho fumana Boc-glycine.

3. Pheta mehato e ka holimo habeli ho kenyelletsa sehlopha sa carboxyl sa glycine ka lihlopha tse peli tse sireletsang tert-butoxycarbonyl ka ho latellana ho fumana Boc-Gly-Gly-Gly-OH.

Lintlha tsa Tšireletseho:

Tšebeliso ea Boc-Gly-Gly-Gly-OH e lokela ho ela hloko litaba tse latelang tsa polokeho:

- Qoba ho kopana le letlalo le mahlo, kaha e ka 'na ea halefisa letlalo le mahlo.

-Apara liatlana tse sireletsang, likhalase le liaparo tse sireletsang nakong ea ts'ebetso.

-E sebetsa sebakeng se nang le moea o motle ho qoba ho hema lerole kapa mouoane oa eona.

-e lokela ho bolokoa hole le mollo, mocheso le oxidant, boloka setshelo se tiisitsoe, se bolokiloe sebakeng se pholileng, se omileng.