Boc-D-Glutamic acid 5-benzyl ester (CAS# 35793-73-8)
Tlhaloso ea Tšireletseho | S22 - U se ke ua hema lerole. S24/25 - Qoba ho kopana le letlalo le mahlo. |
WGK Jeremane | 3 |
Selelekela
Boc-D-Glu(OBzl)-OH(Boc-D-Glu(OBzl)-OH) ke motsoako oa lintho tse phelang. E latelang ke tlhaloso ea sebopeho sa eona, tšebeliso, tlhahiso le tlhaiso-leseling ea polokeho:
Tlhaho:
-Ponahalo: phofo e tšoeu ea kristale
- Foromo ea molek'hule: C20H25NO6
Boima ba 'mele: 379.41
- sebaka se qhibilihang: 118-120 ℃
-Solubility: E qhibiliha ka har'a metsoako e meng ea tlhaho, joalo ka methanol le dichloromethane
Sebelisa:
- Boc-D-Glu(OBzl) -OH e atisa ho sebelisoa tšimong ea motsoako oa lithethefatsi le peptide synthesis.
-E ka sebelisoa e le sehlopha se sireletsang li-peptide ho sireletsa sehlopha se sebetsang sa hydroxyl sa glutamic acid nakong ea ts'ebetso ea ho kopanya ho thibela liketso tse sa rateheng nakong ea karabelo.
Mokhoa oa ho itokisa:
- Boc-D-Glu (OBzl) -OH hangata e lokiselitsoe ke metsoako ea lik'hemik'hale.
-Pele, tert-butoxycarbonyl (Boc) e kenngoa ka molek'hule ea glutamic acid ho hlahisa tert-butoxycarbonyl-D-glutamic acid (Boc-D-Glu).
-Joale, sehlopha sa benzyl (Bzl) se kenngoa sehlopheng sa hydroxyl sa glutamic acid ho theha Boc-D-Glu (OBzl) -OH (Boc-D-Glu (OBzl) -OH).
Lintlha tsa Tšireletseho:
- Boc-D-Glu(OBzl) -OH ke motsoako oa lintho tse phelang, tse ka bakang ho teneha ho itseng le kotsi ho' mele oa motho.
-Nakong ea tšebeliso, ela hloko ho qoba ho kopana le letlalo, mahlo le pampiri ea ho hema.
- Ts'ebetsong ea laboratori kapa tlhahiso ea indasteri, lisebelisoa tse nepahetseng tsa ts'ireletso li lokela ho sebelisoa, joalo ka liatlana, likhalase tse sireletsang le limaske tse sireletsang.
- Boloka hole le mollo le li-oxidizing agents, boloka setshelo se tiisitsoe, 'me u boloke sebakeng se phodileng le se omileng.
Ka kopo hlokomela hore sena ke tlhahisoleseding e akaretsang feela 'me ha e amane le maemo a itseng a liteko le mekhoa e sireletsehileng. Pele o sebelisa komporo ena, ho khothaletsoa ho sheba leqephe la lintlha tsa polokeho ea lik'hemik'hale (MSDS) mme o latele mekhoa e nepahetseng ea ts'ireletso.