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BOC-D-Cyclohexyl glycine (CAS# 70491-05-3)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule C13H23NO4
'Misa oa Molar 257.33
Botenya 1.111±0.06 g/cm3(E boletsoeng esale pele)
Melting Point 75°C(lit.)
Boling Point 407.9±28.0 °C(E boletsoeng esale pele)
Flash point 200.5°C
Solubility Chloroform, Dichloromethane, DMSO, Ethyl Acetate
Khatello ea Mouoane 8.56E-08mmHg ho 25°C
Ponahalo Phofo e tšoeu
Mmala E isang bosoeung
BRN 7689661
pKa 4.01±0.10(E boletsoeng esale pele)
Boemo ba polokelo E tiisitsoe ka sehatsetsing, ka tlas'a -20°C
Refractive Index 1.49
MDL MFCD00133629

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Kotsi le Polokeho

Tlhaloso ea Tšireletseho 24/25 - Qoba ho kopana le letlalo le mahlo.
WGK Jeremane 3
Khoutu ea HS 29242990
Sehlopha sa Likotsi TS'OALANG

 

Selelekela

Boc-alpha-Cyclohexyl-D-glycine(Boc-alpha-Cyclohexyl-D-glycine) ke motsoako oa lintho tse phelang. E latelang ke tlhaloso ea sebopeho sa eona, ts'ebeliso, tokiso le tlhaiso-leseling ea polokeho:

Tlhaho:
Boc-alpha-Cyclohexyl-D-glycine ke ntho e tiileng, hangata ka sebōpeho sa likristale tse tšoeu kapa phofo ea crystalline. E na le boima ba molek'hule ea 247.31 le mokhoa oa lik'hemik'hale oa C14H23NO4. Ke molek'hule ea chiral 'me e na le setsi sa chiral, kahoo se teng ka mokhoa o le mong oa chiral enantiomer le Lee enantiomer.

Sebelisa:
Boc-alpha-Cyclohexyl-D-glycine hangata e sebelisoa e le li-intermediate ho organic synthesis. E phetha karolo ea bohlokoa ho kopantseng li-peptide, lithethefatsi le lihlahisoa tse ling tsa tlhaho. E ka sebelisoa e le sehlopha se sireletsang amino acid ho laola bioavailability le thepa ea pharmacokinetic ea lithethefatsi.

Mokhoa oa ho itokisa:
Boc-alpha-Cyclohexyl-D-glycine hangata e lokisoa ke metsoako ea lik'hemik'hale. Mokhoa o tloaelehileng oa ho itokisa ke karabelo ea D-cyclohexylglycine le N-tert-butoxycarbonylimine (Boc2O). Karabelo hangata e etsoa ka har'a mokelikeli oa lintho tse phelang 'me o laoloa ka mocheso o loketseng. Nakong ea ts'ebetso ea ho kopanya, mehato ea tšireletso e lokela ho nkoa ho netefatsa polokeho ea basebetsi ba laboratori.

Lintlha tsa Tšireletseho:
Boc-alpha-Cyclohexyl-D-glycine ke k'hemik'hale 'me e lokela ho tšoaroa le ho bolokoa hantle. E ka 'na ea halefisa mahlo le letlalo, kahoo ho kopana ka ho toba ho lokela ho qojoa ha ho kopana. Lisebelisoa tse nepahetseng tsa ts'ireletso, joalo ka liatlana tsa lab le likhalase, li lokela ho apesoa ha li sebelisoa. Ka nako e ts'oanang, e lokela ho bolokoa sebakeng se omeletseng, se pholileng, se nang le moea o motle, hole le mollo le lisebelisoa tse tukang.


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