benzyl 3 6-dihydropyridine-1 (2H) -carboxylate (CAS# 66207-23-6)

Selelekela

N-CBZ-1,2,3,6-tetrahydropyridine, eo hape e tsejoang e le carbamate-4-hydroxybenzyl ester-1,2,3,6-tetrahydropyridine, ke motsoako oa lintho tse phelang. Se latelang ke selelekela sa thepa ea eona, tšebeliso, mekhoa ea tlhahiso le tlhaiso-leseling ea polokeho:

Boleng:

- N-Cbz-1,2,3,6-tetrahydropyridine ke 'mala o mosoeu.

- E tsitsitse mocheso oa kamore empa e bola ka mocheso o phahameng.

- E ka qhibiliha ka har'a metsoako e meng ea tlhaho e kang dimethyl sulfoxide le ethanol.

Sebelisa:

- N-Cbz-1,2,3,6-tetrahydropyridine e atisa ho sebelisoa e le sehlopha se sireletsang linthong tsa tlhaho ho sireletsa sehlopha sa amino sehlopheng sa amine. E sireletsa sehlopha sa amino maemong a sa rateheng kapa li-reagents tse ling karabelong.

Mokhoa:

- N-Cbz-1,2,3,6-tetrahydropyridine e ka lokisoa ka amination le acylation. Tetrahydropyridine e sebetsanoa le carbamate ka karabelo ea aminoation ho hlahisa N-amino-1,2,3,6-tetrahydropyridine. Joale, N-amino-1,2,3,6-tetrahydropyridine e sebetsanoa le chloroformate ho theha N-Cbz-1,2,3,6-tetrahydropyridine.

Lintlha tsa Tšireletseho:

- Ho na le lintlha tse fokolang tsa chefo bakeng sa N-Cbz-1,2,3,6-tetrahydropyridine, empa ka kakaretso, e ka 'na ea e-ba le ho teneha le ho chefo ho batho.

- Qoba ho kopana ka ho toba le letlalo le ho hema lerole la lona nakong ea tšebeliso.

- Litlhokomelo tse nepahetseng, tse kang liatlana le lisebelisoa tsa ho phefumoloha, li lokela ho nkoa nakong ea ho tšoara le ho boloka.

- Ha o sebelisa le ho boloka, ka kopo latela litataiso le melaoana e bolokehileng.