6-bromopyridine-2-carboxylic acid ethyl ester (CAS# 21190-88-5)
Matšoao a Kotsi | Xi - Ea halefisang |
Likhoutu tsa Kotsi | 36 - Ho halefisa mahlong |
Tlhaloso ea Tšireletseho | 26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka. |
Selelekela
acid ethyl ester ke motsoako oa organic o nang le foromo ea lik'hemik'hale C8H8BrNO2. Ke mokelikeli o se nang 'mala o nang le monko o khethehileng. Motsoako ona o qhibiliha ka har'a metsoako ea tlhaho e kang ethanol, dimethylformamide le benzene, 'me ha e qhibilihe ka metsing.
acid ethyl ester e na le mefuta e mengata ea likopo ho organic synthesis. E ka sebelisoa e le setsi sa meriana bakeng sa ho kopanya mefuta e mengata ea lithethefatsi le limolek'hule tsa bioactive. Ntle le moo, e ka sebelisoa hape ho karabelo ea Gormperman le karabelo ea li-cross-coupling tsa palladium ka har'a organic synthesis.
Ho na le mekhoa e 'meli e tloaelehileng ea acid ethyl ester:
1. E fumanoa ka karabelo ea 6-bromopyridine le chloroacetate, ebe e kenngoa ka hydrolyzed ka alkali ka mor'a karabelo.
2. Ka 6-bromopyridine le chloroacetic acid ester reaction, acid chloride, ebe o itšoara ka joala ho fumana sehlahisoa.
Ho hlokahala mehato ea tšireletso ha u sebelisa le ho boloka acid ethyl ester. Ke mokelikeli o tukang 'me o lokela ho bolokoa sebakeng se phodileng, se nang le moea o motle, hole le mollo le mocheso o phahameng. Lisebelisoa tse nepahetseng tsa ts'ireletso, joalo ka liatlana tsa lab le likhalase, li lokela ho apesoa nakong ea ts'ebetso. Haeba u noa kapa u kopana le letlalo kapa mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle thuso ea lingaka.