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5-Choro-6-methoxynicotinic acid (CAS# 884494-85-3)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule C7H6ClNO3
'Misa oa Molar 187.58
Botenya 1.430±0.06 g/cm3(E boletsoeng esale pele)
Boling Point 296.7±35.0 °C(E boletsoeng esale pele)
pKa 3.37±0.10 (E boletsoeng esale pele)
Boemo ba polokelo 2-8℃
Refractive Index 1.567

Lintlha tsa Sehlahisoa

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Sehlopha sa Likotsi TS'OALANG

 

Selelekela

5-chloro-6-methoxyniacin ke motsoako oa manyolo. Se latelang ke selelekela sa sebopeho sa eona, tšebeliso, mokhoa oa ho lokisa le tlhaiso-leseling ea polokeho:

 

Thepa: 5-Chloro-6-methoxynicotinic acid ke phofo ea kristale e tšoeu kapa e sa bosoeu. E qhibiliha ka har'a metsoako ea tlhaho e kang ethanol, acetone le methanol ka mocheso oa kamore, 'me e na le ho qhibiliha ho fokolang metsing. E na le litšobotsi tse itseng tsa nicotinic le litšobotsi tsa methoxy.

 

Mokhoa: Motsoako oa 5-chloro-6-methoxynicotinic acid hangata o fumanoa ka chlorination ea methoxynicotinic acid. Mokhoa o tloaelehileng oa ho itokisa ke ho sebelisa methoxyniacin ka thionyl chloride ho hlahisa 5-chloro-6-methoxyniacin.

 

Tlhahisoleseding ea Tšireletseho: 5-Chloro-6-methoxyniacin ka kakaretso e bolokehile tlas'a maemo a tloaelehileng a tšebeliso, empa mehato e nepahetseng e ntse e hlokahala. Qoba ho kopana ka ho toba le letlalo, mahlo, le tsela ea ho hema ho qoba ho teneha kapa ho se thabise. Lisebelisoa tse nepahetseng tsa ts'ireletso tse kang liatlana tsa lab, likhalase le limaske tse sireletsang li lokela ho roaloa ha li sebelisoa. Tlhokomelo e lokela ho nkoa ho qoba likotsi tse bakoang ke ho khantša le motlakase o tsitsitseng nakong ea polokelo le ho sebetsana.


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