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5-bromo-3-cyanopyridine (CAS# 35590-37-5)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule C6H3BrN2
'Misa oa Molar 183.01
Botenya 1.72±0.1 g/cm3(E boletsoeng esale pele)
Melting Point 103-107°C(lebone)
Boling Point 228.8±20.0 °C(E boletsoeng esale pele)
Flash point 92.2°C
Solubility Chloroform (Heated), Ethyl Acetate (Hanyenyane), Methanol (Hanyenyane)
Khatello ea Mouoane 0.0721mmHg ho 25°C
Ponahalo Phofo e tšoeu ea kristale
Mmala Bosehla bo Bosehla ho isa Bosehla
pKa -0.57±0.20(E boletsoeng esale pele)
Boemo ba polokelo Boemo bo sa tsitsang, Mocheso oa Kamore
Refractive Index 1.611
MDL MFCD00174363

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Likhoutu tsa Kotsi R36/37/38 – Ho tena mahlo, tsamaiso ya ho hema le letlalo.
R20/21/22 – E kotsi ka ho hema, ho kopana le letlalo le ha e koetsoe.
Tlhaloso ea Tšireletseho S26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka.
S36 - Apara liaparo tse loketseng tsa tšireletso.
S36/37/39 - Apara liaparo tse loketseng tsa tšireletso, liatlana le tšireletso ea mahlo / sefahleho.
Li-ID tsa UN 3276
WGK Jeremane 3
Khoutu ea HS 29333990
Tsebiso ea Kotsi E tenang
Sehlopha sa Likotsi 6.1
Sehlopha sa ho paka III

 

Selelekela

5-bromo-3-cyanopyridine ke motsoako oa tlhaho o nang le foromo ea lik'hemik'hale C6H3BrN2. Ke kristale e tšoeu ho isa ho bosehla, e qhibilihang ka har'a metsoako e meng ea tlhaho e kang ethanol le dimethyl sulfoxide. Lintlha tse latelang ke tlhaloso e qaqileng ea thepa, tšebeliso, litokisetso le tlhahisoleseding ea polokeho ea 5-bromo-3-cyanopyridine:

 

Tlhaho:

-Ponahalo: Likristale tse tšoeu ho isa ho tse mosehla

- Sebaka sa ho qhibiliha: hoo e ka bang 89-93°C

Sebaka se belang: hoo e ka bang 290-305 ° C

-Botebo: Hoo e ka bang 1.64 g/mL

- Boima ba molek'hule: 174.01g / mol

 

Sebelisa:

5-bromo-3-cyanopyridine e atisa ho sebelisoa e le karolo e bohareng ea motsoako oa manyolo, 'me e na le litšebeliso tsa bohlokoa masimong a motsoako oa lithethefatsi, motsoako oa chefo e bolaeang likokoanyana le motsoako oa dae.

Lisebelisoa tse khethehileng li kenyelletsa:

- Lefapheng la meriana, e ka sebelisoa ho kopanya lithethefatsi tse khahlanong le hlahala, lithethefatsi tse thibelang likokoana-hloko le lithethefatsi tse thibelang likokoana-hloko.

- Lefapheng la chefo e bolaeang likokoanyana, e ka sebelisoa bakeng sa chefo e bolaeang likokoanyana le litlama.

-Lebaleng la lidae, e ka sebelisoa ho kopanya lidae tsa manyolo.

 

Mokhoa oa ho itokisa:

Mokhoa oa ho lokisetsa 5-bromo-3-cyanopyridine o ka etsoa ka mehato e latelang:

1. 3-cyanopyridine e sebetsana le hydrobromic acid tlas'a maemo a alkaline ho hlahisa 5-bromo-3-cyanopyridine.

 

Lintlha tsa Tšireletseho:

Mehato e latelang ea tšireletso e lokela ho nkoa ha u sebelisa 5-bromo-3-cyanopyridine:

-Ke motsoako oa manyolo o halefisang. Qoba ho hema lerōle kapa ho kopana le letlalo le mahlo.

-Ho sebelisoa le ho boloka, ho lokela ho latela mekhoa ea ts'ireletso, ho roala lisebelisoa tsa ho itšireletsa, tse kang li-gloves le likhalase tsa tšireletso.

- Qoba ho kopanya kapa ho kopana le lintho tse kang li-oxidants tse matla le li-acid tse matla ho thibela liketso tse kotsi.

- Boloka sebakeng se nang le moea o kenang hole le malakabe a bulehileng le mehloli ea mocheso.

-Haeba o hema kapa o kopane le letlalo le mahlo, hlatsoa hang-hang ka metsi. Batla thuso ea lingaka haeba ho hlokahala.

 

Ka lebaka la litaba tsa ts'ireletso, tšebeliso le ts'ebetso ea 5-bromo-3-cyanopyridine e lokela ho latela mekhoa e nepahetseng ea laboratori le ho latela melao e nepahetseng ea tšireletso.


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