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4-Hydroxybenzyl alcohol(CAS#623-05-2)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule C7H8O2
'Misa oa Molar 124.14
Botenya 1.1006 (khakanyo e fosahetseng)
Melting Point 114-122°C(lebone)
Boling Point 251-253°C
Flash point 251-253°C
JECFA Nomoro 955
Ho qhibiliha ha Metsi E qhibiliha ka metsing (6.7 mg/ml ka 20°C), dioxane (100 mg/ml), 1N NaOH (50 mg/ml), DMSO, le methanol.
Solubility E qhibiliha ka methanol, ethanol, DMSO le metsoako e meng ea tlhaho.
Khatello ea Mouoane 0.0104mmHg ho 25°C
Ponahalo Pinki, beige (phofo ea kristale)
Mmala Pinki ho beige
BRN 1858967
pKa pK1:9.82 (25°C)
Boemo ba polokelo Boloka ka tlase ho +30°C.
E hloahloa E Mamela Leseli/E Mamela Moya
Refractive Index 1.5035 (khakanyo)
MDL MFCD00004658
Thepa ea 'Mele le ea Lik'hemik'hale sebaka se qhibilihang ke 110-112°C
Sebelisa E sebedisoa joalo ka mahareng ho organic synthesis
Thuto ea in vitro 4-Hydroxybenzyl joala e thibela ho ata ha lisele tsa eEND2 le ho hatella ho falla ha lisele tsa eEND2, tse tsamaeang le ho thibela ho tsosolosoa ha actin filament. 4-Hydroxybenzyl joala e baka lefu la apoptotic ea lisele tsa tumor.
Thuto ea in vivo 4-Hydroxybenzyl joala e na le ts'ebetso ea antiangiogenic, anti-inflammatory le anti-nociceptive mohlomong ka ts'ebetso ea eona e tlase-taolo mabapi le tlhahiso ea NO. 4-Hydroxybenzyl alcohol (200 mg / kg) e thibela ka katleho kholo le angiogenesis ea ho hlahisa lihlahala. 4-Hydroxybenzyl joala e matlafatsa kotsi ea ischemic e bakoang ke "cerebral ischemia" ea nakoana ka har'a likhoto, 'me phello ena ea neuroprotective e kanna ea amana le tsela ea apoptosis.

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Matšoao a Kotsi Xi - Ea halefisang
Likhoutu tsa Kotsi R36 – Ho teneha mahlong
R36/37/38 – Ho tena mahlo, tsamaiso ya ho hema le letlalo.
Tlhaloso ea Tšireletseho S26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka.
S24/25 - Qoba ho kopana le letlalo le mahlo.
S36 - Apara liaparo tse loketseng tsa tšireletso.
WGK Jeremane 3
RTECS DA4796800
LIKHOUTU FLUKA BRAND F 8-9-23
Khoutu ea HS 29072900
Tsebiso ea Kotsi Ho teneha / Lula u Batse / Moea o Mamela / Khanya e Mamela

 

Selelekela

Hydroxybenzyl alcohol ke motsoako oa tlhaho o nang le sebopeho sa lik'hemik'hale sa C6H6O2, se tsejoang ka hore ke phenol methanol. Mona ke tse ling tsa thepa e tloaelehileng, ts'ebeliso, mekhoa ea ho lokisa le tlhaiso-leseling ea polokeho mabapi le joala ba hydroxybenzyl:

 

Boleng:

Ponahalo: Mokelikeli o tiileng ho isa ho o mosehla o se nang mmala.

Solubility: Ho qhibiliha ka har'a metsoako ea tlhaho e kang metsi, joala le ether.

 

Sebelisa:

Li-preservatives: E na le lintho tse thibelang likokoana-hloko le likokoana-hloko, 'me joala ea hydroxybenzyl e boetse e sebelisoa e le se sireletsang patsi.

 

Mokhoa:

Hydroxybenzyl alcohol hangata e hlahisoa ke karabelo ea para-hydroxybenzaldehyde ka methanol. Karabelo e ka hlahisoa ke sesebelisoa sa oxidizing, joalo ka catalyst Cu(II.) kapa ferric chloride(III.). Karabelo ka kakaretso e etsoa ka mocheso oa kamore.

 

Lintlha tsa Tšireletseho:

Joala ba Hydroxybenzyl bo na le chefo e tlase, empa tlhokomelo e ntse e hlokahala ho bo sebetsana ka mokhoa o sireletsehileng.

Tabeng ea ho kopana le letlalo, hlatsoa hang-hang ka metsi a mangata. Haeba o koetsoe, batla thuso ea bongaka hang-hang.

Ho kopana le li-oxidants, acid, le phenols ho lokela ho qojoa nakong ea ts'ebetso le polokelo ho thibela liketso tse kotsi.

Ha e sebelisoa kapa e bolokoa, e lokela ho behoa hole le malakabe a bulehileng kapa mocheso o phahameng ho thibela mollo.


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