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4-Chloro-2-fluorobenzoic acid (CAS# 446-30-0)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule C7H4ClFO2
'Misa oa Molar 174.56
Botenya 1.4016 (khakanyo)
Melting Point 204-208 °C (hote.)
Boling Point 274.7±20.0 °C(E boletsoeng esale pele)
Flash point 119.9°C
Ho qhibiliha ha Metsi e sa qhibidihang
Khatello ea Mouoane 0.00259mmHg ho 25°C
Ponahalo Phofo ea kristale
BRN 973358
pKa 3.04±0.10(E boletsoeng esale pele)
Boemo ba polokelo E tiisitsoe ka ho omme, Mocheso oa Kamore
MDL MFCD00042468
Thepa ea 'Mele le ea Lik'hemik'hale Likristale tse tšoeu kapa tse tšoeu. Sebaka se qhibilihang ke 206-210 ℃.
Sebelisa E sebelisoa e le chefo e bolaeang likokoanyana, li-intermediate tsa meriana

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Kotsi le Polokeho

Likhoutu tsa Kotsi R36/37/38 – Ho tena mahlo, tsamaiso ya ho hema le letlalo.
R22 – E kotsi ha e kwetswe
Tlhaloso ea Tšireletseho S26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka.
S36 - Apara liaparo tse loketseng tsa tšireletso.
S37/39 - Apara liatlana tse loketseng le tšireletso ea mahlo / sefahleho
WGK Jeremane 3
Khoutu ea HS 29163990
Sehlopha sa Likotsi TS'OALANG

446-30-0 - Boitsebiso ba Litšupiso

Kopo 4-chloro-2-fluoro-benzoic acid ke karolo ea bohlokoa lipakeng tsa organic synthesis le meriana, e sebelisoa haholo ho li-fungicides, ATX inhibitors, NHE3 inhibitors le bahanyetsi ba NMDA receptor.
Lintho tsa lik'hemik'hale likristale tse tšoeu kapa tse bosoeu. Sebaka se qhibilihang ke 206-210 °c.
Kopo se sebedisoang joalo ka sebolaya dikokonyana le meriana ya mahareng

 

Kenyelletso e khutšoanyane
4-Chloro-2-fluorobenzoic acid ke motsoako oa lintho tse phelang. Se latelang ke selelekela sa thepa ea eona, tšebeliso, mekhoa ea tlhahiso le tlhaiso-leseling ea polokeho:

Boleng:
4-Chloro-2-fluorobenzoic acid ke kristale e tiileng, hangata e se nang 'mala kapa e mosehla. Ha e fetohe mocheso oa kamore. E na le tatso e nkhang hamonate 'me e ka qhibiliha ka har'a metsoako ea lintho tse phelang tse kang methanol, ethanol, methylene chloride, joalo-joalo.

Sebelisa:
4-Chloro-2-fluorobenzoic acid e na le mefuta e mengata ea lisebelisoa ho indasteri ea lik'hemik'hale. Hangata e sebelisoa e le thepa ea ho qala kapa e bohareng ba organic synthesis. E ka boela ea sebelisoa e le phepelo ea li-catalysts le lisebelisoa tsa elektroniki.

Mokhoa:
4-Chloro-2-fluorobenzoic acid e ka fumanoa ka chlorination ea p-fluorobenzoic acid. Ka kakaretso, hydrogen chloride kapa chlorous acid e ka itšoara ka thionyl chloride kapa sulfinyl chloride tlas'a maemo a acidic, e lateloa ke ho itšoara ka hydrogen fluoride ho fumana 4-chloro-2-fluorobenzoic acid.

Lintlha tsa Tšireletseho:
Mehato e latelang ea tšireletso e lokela ho nkoa ha u tšoara 4-chloro-2-fluorobenzoic acid: qoba ho kopana le letlalo le mahlo, 'me u ele hloko mehato ea tšireletso e kang ho roala likhalase tse sireletsang le liatlana. E lokela ho etsoa sebakeng se nang le moea o motle ho thibela ho hema kapa ho metsa. Qoba ho kopana le lintho tse tukang 'me u ipolokele hole le malakabe a bulehileng kapa mocheso o phahameng. E tlameha ho tiisoa ka thata ha e sebelisoa kapa e bolokoa le hole le li-acids, bases le li-oxidants. Ha ho e-na le ho lutla, mehato e loketseng ea tšohanyetso e lokela ho nkoa, e kang ho monya metsi ka desiccant kapa ho e hloekisa ka adsorbent e loketseng ea lik'hemik'hale.

 

 


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