4-[(4-Hydroxy-2-pyrimidinyl)amino]benzonitrile(CAS# 189956-45-4)

Foromo ea limolek'hule	C11H8N4O
'Misa oa Molar	212.21
Botenya	1.31±0.1 g/cm3(E boletsoeng esale pele)
Melting Point	>300°C
Boling Point	399.7°C ho 760 mmHg
Flash point	195.6°C
Solubility	DMSO (Hanyane), Methanol (Hanyenyane)
Khatello ea Mouoane	0-0Pa ho 20-25 ℃
Ponahalo	Tiileng
Mmala	Pale Brown ho Brown
pKa	8.66±0.40(E boletsoeng esale pele)
Boemo ba polokelo	2-8°C
Refractive Index	1.67

Lintlha tsa Sehlahisoa

LogP	0.9 ho pH6.6
tshebediso	4 - [(4-hydroxy-2-pyrimidinyl) amino] benzonitrile e ka sebelisoa e le setsi sa ho kopanya lintho tse phelang le motsoako oa meriana, 'me e ka sebelisoa ho laboratori ea Organic synthesis process le lipatlisiso tsa lik'hemik'hale le tsa meriana le tsoelo-pele.
tokisetso	boima ba 2-(methylthio) pyrimidine -4(3H)-one (3g,21mmol) le 4-aminobenzonitrile (2.99g,25mmol) ka botlolong e chitja e 50mL, e sirelelitsoeng ke naetrojene, butle-butle e futhumatsoa ho 180 ℃, mme e itšoara ka 8 lihora. Kamora hore karabelo e pholile, 20mL ea acetonitrile e eketsoa bakeng sa kalafo ea ultrasonic, filtration, kaka ea sefahla e hlatsuoa ka acetonitrile, ha ho masala a 4-aminobenzonitrile a bonoang ke TLC, 'me bosehla bo bobebe bo fumanoeng ka ho omisa kuku ea sefahla ke 4-( (4-oxo -1, 6-dihydropyrimidine -2-yl) amino) benzonitrile e nang le kotulo ea 73.6%.