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sehlahisoa

3-methyl-2-oxobutyric acid (CAS# 759-05-7)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule C5H8O3
'Misa oa Molar 116.12
Botenya 0.9968
Melting Point 31.5 ℃
Boling Point 170.5 ℃
JECFA Nomoro 631
Ho qhibiliha ha Metsi 400.6g/L(20 ºC)
pKa 2.57±0.54(E boletsoeng esale pele)
Boemo ba polokelo 2-8°C
Refractive Index 1.3850
Thuto ea in vitro 3-Methyl-2-oxobutanoic acid (alpha-Ketoisovaleric acid) ke selelekela sa pantothenic acid ho Escherichia coli. 3-Methyl-2-oxobutanoic acid (alpha-Ketoisovaleric acid) e ntlafatsa alpha-ketoisocaproic acid le alpha-keto-beta-methyl-n-valeric acid, empa e fokotsa li-amino acid tse tsamaellanang, 'me e baka ho fokotseha hoa pele ha ornithine. keketseho ea morao ea plasma arginine.
Thuto ea in vivo 3-Methyl-2-oxobutanoic acid (alpha-Ketoisovaleric acid) e baka ho ferekana ka mekhoa ea GABAergic le glutamatergic ho likhoto.

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

 

Selelekela

3-Methyl-2-oxobutyric acid, e tsejoang hape e le tert-butoxypropionic acid, TBAOH, ke motsoako oa lintho tse phelang.

 

Boleng:

3-Methyl-2-oxobutyric acid ke mokelikeli o mosehla o mosehla o se nang 'mala o nang le monko o ikhethang. E ka qhibiliha ka har'a metsi le lihlahisoa tse ngata tsa tlhaho, empa ha e khone ho qhibiliha ka har'a lihlapolli tse seng tsa polar tse kang petroleum ethers.

 

Sebelisa:

3-Methyl-2-oxobutyric acid e atisa ho sebelisoa e le alkali catalyst ho organic synthesis, haholo-holo ka liphetoho tse ling. E ka susumetsa maikutlo a kang esterification, etherification, amidation, olefin phaella, joalo-joalo. E ka boela ea sebelisoa e le mokelikeli-mohato oa ho susumetsa maikutlo a kang oxidation, hydrogenation, le alkydation.

 

Mokhoa:

3-Methyl-2-oxobutyric acid e ka fumanoa ka ho arabela propanol ka sodium tert-butoxide (kapa tert-butanol le sodium hydroxide). Mohato o ikhethileng ke ho arabela propanol ka tert-butyl sodium oxide ka mocheso o loketseng, ebe sehlahisoa se fumanoa ka ho tima.

 

Lintlha tsa Tšireletseho:

3-Methyl-2-oxobutyric acid e ea halefisa ebile e senya 'me e lokela ho qojoa hore e se kopane le letlalo, mahlo le pampiri ea ho hema. Li-gloves tse sireletsang, likhalase le limaske li lokela ho apesoa nakong ea ts'ebeliso. Haeba motho a ka kopana ka phoso, hlatsoa ka metsi a mangata 'me u batle ngaka hang-hang. E lokela ho bolokoa sebakeng se phodileng, se nang le moea, hole le mollo le li-oxidants.


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