3-Chloro-5-(trifluoromethyl)pyridine (CAS# 85148-26-1)
| Likhoutu tsa Kotsi | R20/21/22 – E kotsi ka ho hema, ho kopana le letlalo le ha e koetsoe. R36/37/38 – Ho tena mahlo, tsamaiso ya ho hema le letlalo. R25 – E chefo ha e koetsoe |
| Tlhaloso ea Tšireletseho | S26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka. S36/37/39 - Apara liaparo tse loketseng tsa tšireletso, liatlana le tšireletso ea mahlo / sefahleho. S36 - Apara liaparo tse loketseng tsa tšireletso. S45 – Ha ho ka etsahala kotsi kapa ha o ikutlwa o sa phele hantle, batla keletso ya bongaka hanghang (bontsha leibole neng kapa neng ha ho kgoneha.) |
| Li-ID tsa UN | UN 2811 6.1 / PGIII |
| WGK Jeremane | 3 |
| Tsebiso ea Kotsi | E tenang |
| Sehlopha sa Likotsi | MOHALE-HOLO-H |
| Sehlopha sa ho paka | III |
Selelekela
3-choro-5-(trifluoromethyl)pyridine ke motsoako oa organic o nang le foromo ea lik'hemik'hale C≡H₂ ClFΛ N. Ke mokelikeli o mosehla o mosehla o se nang 'mala o nang le monko o monate. Lintlha tse latelang ke tlhaloso ea tlhaho, tšebeliso, litokisetso le tlhahisoleseding ea polokeho ea 3-choro-5-(trifluoromethyl)pyridine:
Tlhaho:
- Boima ba 'mele: 1.578 g/mL
Sebaka se belang: 79-82 ℃
- Sebaka se qhibilihang: -52.5 ℃
-Solubility: E qhibiliha ka har'a metsoako ea tlhaho e kang ethanol, ether le dichloromethane, e qhibilihang hanyenyane metsing.
Sebelisa:
-E le li-reagents le li-intermediates ka har'a motsoako oa manyolo, tse sebelisoang ha ho etsoa chefo e bolaeang likokoanyana, lithethefatsi le metsoako e meng ea manyolo.
- Bakeng sa lipatlisiso lefapheng la bongaka, joalo ka ha ho kopantsoe lithethefatsi tse khahlanong le mofetše le li-biomarker.
Mokhoa oa ho itokisa:
3-chloro-5-(trifluoromethyl)pyridine e ka lokisoa ka mekhoa e' meli e latelang:
1. Ho sebelisa pyridine e le lisebelisoa tse tala, karabelo ea chlorination e etsoa ka pel'a hydrochloric acid, 'me joale karabelo ea trifluoromethylation e etsoa ka pel'a sodium trifluoromethylate.
2. Ho sebelisa 3-picolinic acid e le lihlahisoa tse tala, chlorination reaction e etsoa ka pel'a thionyl chloride, 'me joale karabelo ea trifluoromethylation e etsoa ka pel'a trifluoromethyl mercaptan.
Lintlha tsa Tšireletseho:
- 3-chloro-5-(trifluoromethyl)pyridine e ea tena 'me e ka baka ho teneha ha ho kopana le letlalo le mahlo. Hoa hlokahala ho apara mehato e nepahetseng ea ho itšireletsa ha u sebelisa, joalo ka ho roala likhalase tse sireletsang, liatlana le liaparo tse sireletsang.
- Qoba ho hema mouoane oa eona 'me u netefatse hore ts'ebetso e etsoa sebakeng se nang le moea o motle.
-Ha u e boloka, e boloke ka sejaneng se tiisitsoeng, hole le mollo le li-oxidizing agents.
-Ha u lahla litšila, li tšoare le ho li lahla ho latela melao ea lehae.
-Ka kopo, sheba Leqephe la Tšireletso la Tšireletso (SDS) bakeng sa boitsebiso bo eketsehileng ba polokeho.
