3-Bromo-2-hydroxy-5-(trifluoromethyl)pyridine (CAS# 76041-73-1)
| Likhoutu tsa Kotsi | 25 - Chefo haeba e koetsoe |
| Tlhaloso ea Tšireletseho | 45 - Haeba ho ka etsahala kotsi kapa ha u ikutloa u sa phele hantle, batla keletso ea bongaka hang-hang (bontša lengolo neng le neng ha ho khoneha.) |
| Khoutu ea HS | 29333999 |
| Sehlopha sa Likotsi | TS'OALANG |
Selelekela
2 (1H) -Pyridinone,3-bromo-5-(trifluoromethyl)-(2(1H)-Pyridinone,3-bromo-5-(trifluoromethyl)-) ke motsoako oa lintho tse phelang. E na le foromo ea molek'hule ea C6H3BrF3NO le boima ba molek'hule ea 218.99g / mol. E latelang ke tlhaloso ea sebopeho sa eona, tšebeliso, tlhahiso le tlhaiso-leseling ea polokeho:
Tlhaho:
-Ponahalo: 2 (1H) -Pyridinone, 3-bromo-5- (trifluoromethyl) -e tiileng, hangata e tšoeu ho isa likristale tse mosehla.
- Sebaka sa ho qhibiliha: Sebaka sa eona se qhibilihisang ke 90-93°C.
-Solubility: 2 (1H) -Pyridinone,3-bromo-5-(trifluoromethyl) -e na le ho qhibiliha ho itseng ho li-solvents tse tloaelehileng, tse kang ethanol, ether le chloroform.
Sebelisa:
- Lipatlisiso tsa lik'hemik'hale: 2 (1H) -Pyridinone, 3-bromo-5- (trifluoromethyl) -e ka sebelisoa e le reagent kapa e bohareng ba motsoako oa lintho tse phelang. Hangata e sebelisoa ho etsa skeleton ea limolek'hule tse rarahaneng tsa lintho tse entsoeng ka tšepe.
-Ntšetso-pele ea lithethefatsi: Ka lebaka la sebopeho sa eona se khethehileng le thepa ea lik'hemik'hale, e ka 'na ea phetha karolo ea bohlokoa ho nts'etsopele ea lithethefatsi, tse kang li-anti-cancer agents, li-antiviral agents, joalo-joalo.
Mokhoa oa ho itokisa:
2 (1H) -Pyridinone,3-bromo-5-(trifluoromethyl) -e ka etsoa ka mekhoa e sa tšoaneng, e latelang ke e' ngoe ea mekhoa e tloaelehileng ea ho kopanya:
2-hydroxyl pyridine e sebetsa le magnesium bromide ho hlahisa 2-hydroxyl -3-bromopyridine. Joale 3-bromopyridine e sebetsanoa le fluoromethyllithium ho fana ka 2(1H) -Pyridinone,3-bromo-5-(trifluoromethyl)-. Ka kakaretso, motsoako o etsoa ka har'a motsoako oa lintho tse phelang, joalo ka dimethyl sulfoxide, le ka mocheso o tlase.
Tlhahisoleseding ea Polokeho: Polokeho ea
- 2 (1H) -Pyridinone,3-bromo-5-(trifluoromethyl) -ha e e-s'o hlahlojoe ka ho hlaka, kahoo tlhokomelo e lokela ho nkoa ha e tšoara le ho boloka. Basebelisi ba eletsoa ho apara lisebelisoa tse nepahetseng tsa ts'ireletso, joalo ka liatlana tsa lab le ts'ireletso ea mahlo. Qoba ho hema lerole la yona kapa ho ama letlalo.
-Ka lebaka la thepa ea eona ea lik'hemik'hale, e ka 'na ea e-ba chefo ho tikoloho ea metsi. Ka kopo latela mekhoa e nepahetseng ea ts'ireletso ha u sebelisa, ho qoba ho tsoa ha eona ka metsing.
-Ha u sebelisa motsoako ona, ho kgothaletswa ho sebetsa tlas'a maemo a laboratori a nang le moea o motle ho qoba ho inhalation ea li-volatile tsa eona. Haeba motho a tšolohile kapa a hema ka phoso, batla thuso ea bongaka hang-hang.
