2-Methyl-4-trifluoromethyl-thiazole-5-carboxylic acid (CAS# 117724-63-7)
2-methyl -4- (trifluoromethyl) thiazole-5-carboxylic acid ke motsoako oa manyolo o nang le motsoako oa lik'hemik'hale C6H4F3NO2S.
Motsoako o na le litšobotsi tse latelang:
1. Ponahalo: kristale e se nang mebala kapa phofo e tšoeu ea kristale.
2. Sebaka se qhibilihang: hoo e ka bang 70-73°C.
3. ho qhibiliha: ho qhibiliha ka har'a metsoako e meng ea tlhaho, e kang ethanol, dimethyl sulfoxide le chloroform, e qhibilihang hanyenyane metsing.
Ts'ebeliso ea mantlha ea 2-methyl -4-(trifluoromethyl) thiazole-5-carboxylic acid e kenyelletsa:
1. Tšimo ea meriana: e le setsi sa meriana, se ka sebelisoa bakeng sa ho kopanya mefuta e sa tšoaneng ea lithethefatsi.
2. Tšimo ea chefo e bolaeang likokoanyana: e sebelisoang hangata ha ho etsoa chefo e ncha, meriana e bolaeang limela le tse ling tse bolaeang likokoanyana.
2-methyl -4-(trifluoromethyl) thiazole -5-carboxylic acid mekhoa ea ho lokisa haholo-holo e latelang:
1. amide le formaldehyde condensation reaction: formic acid le ethyl ester condensation ho hlahisa acid anhydride, 'me ka mor'a moo ka amine condensation reaction ho fumana sehlahisoa se lebisitsoeng.
2. Hydrogenation reaction tlas'a acid catalysis: 2-methyl -4- (trifluoromethyl) thiazole-5-carboxylic acid e itšoara ka hydrogen tlas'a acid catalysis ho fumana sehlahisoa se lebisitsoeng.
Mabapi le tlhahisoleseling ea polokeho, lintlha tsa toxicological le polokeho ea 2-methyl -4-(trifluoromethyl) thiazole-5-carboxylic acid ha li tlalehoe hangata, ka hona hoa hlokahala ho nka mehato e itseng ea ts'ireletso nakong ea ts'ebetso ea laboratori, joalo ka ho roala likhalase tse sireletsang le liatlana, ho etsa bonnete ba hore ts'ebetso ea liteko e etsoa sebakeng se nang le moea o motle. Ho phaella moo, motsoako o ka 'na oa senya le ho halefisa,' me tlhokomelo e lokela ho nkoa ho thibela ho kopana le letlalo le ho hema. Nakong ea tšebeliso le polokelo, mekhoa ea ts'ireletso ea lik'hemik'hale e lokela ho lateloa le ho bolokoa sebakeng se omileng, se nang le moea o hloekileng le se lefifi. Ha o sebetsana le ho lahla kompone ena, latela melaoana e amehang ea lehae le litataiso tse bolokehileng tsa ts'ebetso. Haeba ka phoso u kopana le ntho eo, hlatsoa hang-hang ka metsi a mangata 'me u batle thuso ea bongaka.
