2-Chloro-3-fluoro-5-methylpyridine (CAS# 34552-15-3)
Matšoao a Kotsi | Xi - E halefisang |
Sehlopha sa Likotsi | MOQEBI |
Selelekela
Ke motsoako oa tlhaho o nang le foromo ea lik'hemik'hale ea C6H5ClFN. E latelang ke tlhaloso ea thepa, tšebeliso, tokiso le tlhaiso-leseling ea polokeho ea komporo:
Tlhaho:
-Ponahalo: Ke mokelikeli o se nang 'mala ho isa ho o mosehla o khanyang.
- Sebaka se belang: hoo e ka bang 126-127°C.
- Boima: hoo e ka bang 1.36g/cm³.
-Solubility: E qhibiliha ka har'a metsoako e mengata ea lintho tse phelang, tse kang ethanol, ether le dimethylformamide.
Sebelisa:
-e sebelisoa haholo e le motsoako oa motsoako oa tlhaho 'me e ka sebelisoa ho kopanya metsoako e meng ea tlhaho.
-E ka boela ea sebelisoa e le ntho e qalang bakeng sa motsoako oa lithethefatsi, motsoako oa chefo e bolaeang likokoanyana le motsoako oa dae.
Mokhoa oa ho itokisa:
-kapa e ka lokisoa ke karabelo ea halogenation ea pyridine. Ntlha ea pele, pyridine le acetic acid li kena karabelo ea chlorination ho hlahisa 2-chloropyridine. Joale 2-chloropyridine e fetoloa 2-chloro-3-fluoropyridine ka karabelo ea fluorination. Qetellong, 2-chloro-3-fluoropyridine e ne e le methylated e sebelisa methylation reaction.
Lintlha tsa Tšireletseho:
-ke motsoako o halefisang o ka khopisang mahlo le letlalo.
-Nakong ea ts'ebeliso le ho ts'oaroa, mehato e nepahetseng ea ts'ireletso e lokela ho nkoa, ho kenyelletsa ho roala likhalase tse sireletsang le liatlana.
- Qoba ho hema mouoane oa motsoako 'me u netefatse hore o sebelisoa sebakeng se nang le moea o motle.
-Ha u boloka le ho tšoara, qoba mollo le li-oxidizing agents ho qoba kotsi ea mollo le ho phatloha.
-Nakong ea tšebeliso, tlhokomelo e lokela ho lefshoa ho latela mekhoa le melaoana e nepahetseng ea ts'ebetso ea ts'ireletso.