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sehlahisoa

2-Bromo-5-(trifluoromethyl)pyridine (CAS# 50488-42-1)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule C6H3BrF3N
'Misa oa Molar 225.99
Botenya 1.707±0.06 g/cm3(E boletsoeng esale pele)
Melting Point 44-48 °C
Boling Point 78 °C
Flash point 78-81°C/30mm
Solubility E qhibiliha ka methanol le ethanol.
Khatello ea Mouoane 0mmHg ho 25°C
Ponahalo Nale e mosehla e khanyang
pKa -1?+-.0.10(E boletsoeng esale pele)
Boemo ba polokelo Boloka sebakeng se lefifi, se tiisitsoe moo ho omileng, Mocheso oa Kamore
Refractive Index 1.572
MDL MFCD00153086
Thepa ea 'Mele le ea Lik'hemik'hale Likristale tse se nang bosoeu
Sebelisa Substrate bakeng sa palladium-catalyzed α-arylation ea li-reagents tsa Refomatsky

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Likhoutu tsa Kotsi R25 – E chefo ha e koetsoe
R36/37/38 – Ho tena mahlo, tsamaiso ya ho hema le letlalo.
R20/21/22 – E kotsi ka ho hema, ho kopana le letlalo le ha e koetsoe.
Tlhaloso ea Tšireletseho S26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka.
S36/37/39 - Apara liaparo tse loketseng tsa tšireletso, liatlana le tšireletso ea mahlo / sefahleho.
S22 - U se ke ua hema lerole.
S36 - Apara liaparo tse loketseng tsa tšireletso.
Li-ID tsa UN UN 2811 6.1/PG 3
WGK Jeremane 3
Khoutu ea HS 29333990
Sehlopha sa Likotsi TS'OALANG
Sehlopha sa ho paka

 

Selelekela

2-Bromo-5-(trifluoromethyl)pyridine (eo hape e tsejoang e le BTFP) ke motsoako oa tlhaho. Se latelang ke selelekela sa sebopeho sa eona, tšebeliso, mokhoa oa ho lokisa le tlhaiso-leseling ea polokeho:

 

Boleng:

- Ponahalo: E tšoeu e tiileng

- Boima ba molek'hule: 206.00 g / mol

- Sollubility: BTFP e qhibiliha habonolo ka har'a metsoako ea tlhaho (mohlala, joala, ethers, ketone) empa ha e qhibilihe ka metsing.

 

Sebelisa:

- E le motsoako oa mahareng: BTFP e sebelisoa haholo ho lokiseng li-intermediate tsa organic synthesis, joalo ka metsoako ea pyridine, metsoako e nkhang hamonate, joalo-joalo.

- Joaloka ligand: BTFP e ka sebelisoa e le ligand bakeng sa li-complexes tsa tšepe 'me e kenya letsoho liketsong tse fapa-fapaneng tsa catalytic le ho lokisetsa lisebelisoa tse sebetsang.

- Joalo ka reagent: BTFP e bapala karolo ea bohlokoa ho organic synthesis, joalo ka coupling reaction, substitution reaction, le karabelo ea phokotso.

 

Mokhoa:

2-Bromo-5-(trifluoromethyl)pyridine e ka etsoa ka mehato e latelang:

1. Hlakola 2-amino-5-(trifluoromethyl)pyridine ka mokelikeli o loketseng oa lintho tse phelang, tse kang joala kapa ketone.

2. Kenya metsoako ea bromine (mohlala, hydrogen bromide, methyl bromide).

3. Etsa karabelo ka mocheso o nepahetseng le maemo a susumetsang.

4. Sefa sehlahisoa 'me u etse crystallization le tlhoekiso.

 

Lintlha tsa Tšireletseho:

- BTFP e ka tiisa kapa ea khanya ka mocheso o tlase, ka kopo boloka mocheso oa kamore 'me u qobe kristale.

- Apara liatlana tse sireletsang le likhalase nakong ea ts'ebetso ho qoba ho kopana le letlalo le mahlo.

- Qoba ho hema lerōle kapa mouoane oa eona, kaha BTFP e ka 'na ea e-ba le phello e halefisang tseleng ea ho hema.

- Sheba bukana ea tšireletso e amehang ha u sebelisa kapa u tšoara BTFP, 'me u lahle litšila le lihlapolli ka nepo.


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  • E 'ngoe:

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