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2-BROMO-3-METHOXYPYRIDINE (CAS# 24100-18-3)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule C6H6BrNO
'Misa oa Molar 188.02
Botenya 1.530±0.06 g/cm3(E boletsoeng esale pele)
Melting Point 45-49 °C (hote.)
Boling Point 233.4±20.0 °C(E boletsoeng esale pele)
Flash point >230°F
Solubility Dichloromethane
Khatello ea Mouoane 0.0852mmHg ho 25°C
Ponahalo Phofo ea Crystalline
Mmala E tšoeu ho ea ho tranelate
pKa -0.51±0.10(E boletsoeng esale pele)
Boemo ba polokelo Boloka sebakeng se lefifi, se tiisitsoe moo ho omileng, Mocheso oa Kamore
Refractive Index 1.542
MDL MFCD01570896

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Matšoao a Kotsi Xn - E Kotsi
Likhoutu tsa Kotsi R22 – E kotsi ha e kwetswe
R37/38 – E tenang tsamaiso ya ho hema le letlalo.
R41 – Kotsi ya tshenyo e kgolo mahlong
Tlhaloso ea Tšireletseho S26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka.
S39 - Apara ts'ireletso ea mahlo / sefahleho.
WGK Jeremane 3
Khoutu ea HS 29333990

 

Selelekela

2-bromo-3-methoxypyridine ke motsoako oa tlhaho o nang le foromo ea lik'hemik'hale C6H6BrNO. E latelang ke tlhaloso ea sebopeho sa eona, ts'ebeliso, tokiso le tlhaiso-leseling ea polokeho:

 

Tlhaho:

-Ponahalo: mokelikeli o se nang 'mala

-Solubility: E qhibiliha ka har'a ethanol e anhydrous le lihlapolli tsa Ether

Sebaka se belang: 167-169 ° C

- Boima ba 'mele: 1.568 g/mL

 

Sebelisa:

2-bromo-3-methoxypyridine e na le lits'ebetso tse itseng lefapheng la k'hemistri:

-E le ea mahareng: e ka sebelisoa ho kopanya metsoako e meng ea manyolo, joalo ka lithethefatsi, chefo e bolaeang likokoanyana le dae.

-Organic synthesis: E ka nka karolo liketsong tse fapaneng tse fapaneng, joalo ka karabelo ea li-electrophilic substitution, karabelo ea condensation, jj.

 

Mokhoa:

2-bromo-3-methoxypyridine synthesis mekhoa haholo-holo e latelang:

1. Ka karabelo ea 3-methoxypyridine le bromine: 3-methoxypyridine e itšoara ka bromine le ho futhumala tlas'a maemo a alkaline ho fumana sehlahisoa sa 2-bromo-3-methoxypyridine.

2. Ka karabelo ea pyridine le 2-Bromo methyl ether: pyridine le 2-Bromo methyl ether reaction, tlas'a maemo a loketseng bakeng sa ho futhumatsa kapa ho sebelisa catalyst ho hlahisa sehlahisoa se lakatsehang.

 

Lintlha tsa Tšireletseho:

Tšireletso ea 2-bromo-3-methoxypyridine e hloka tlhokomelo. Lintlha tse latelang ke tse ling tsa ts'ireletso:

- Qoba ho hema, ho kopana le letlalo, kapa ho kena mahlong. Apara lisebelisoa tse nepahetseng tsa ts'ireletso tse kang liatlana, likhalase le lithebe tsa sefahleho nakong ea ts'ebeliso.

-Ha e boloka, e lokela ho behoa sebakeng se nang le moea o motle, hole le mollo le li-oxidizing agents.

- Bala leqephe la lintlha tsa polokeho tse amehang ka hloko pele u li sebelisa 'me u le sebelise ho latela mekhoa e nepahetseng ea ts'ebetso.

 


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