2-(5-aminopyrazin-2-yl)propan-2-ol (CAS# 1174231-20-9)
Ho hlahisa boqapi ba rona ba morao-rao sebakeng sa li-intermediate tsa meriana: 2-(5-aminopyrazin-2-yl)propan-2-ol (CAS # 1174231-20-9). Motsoako ona oa sejoale-joale o etselitsoe ho fihlela litlhoko tse ntseng li tsoela pele tsa bafuputsi le bahlahisi ba indasteri ea meriana, e fana ka mohaho o nang le mekhoa e mengata ea ho haha motsoako oa mefuta e mengata ea limolek'hule tsa bioactive.
2-(5-aminopyrazin-2-yl) propan-2-ol e khetholloa ke sebopeho sa eona se ikhethang sa limolek'hule, se nang le lesale la pyrazine le ntlafatsang ts'ebetso ea eona ea ho sebetsa le ho sebetsa. Motsoako ona o bohlokoa haholo bakeng sa karolo ea ona ho nts'etsopele ea li-agent tse ncha tsa kalafo, haholo-holo mafapheng a oncology le mafu a tšoaetsanoang. Bokhoni ba eona ba ho sebetsa e le senotlolo sa bohareng bo lumella hore ho be le motsoako o sebetsang oa limolek'hule tse rarahaneng, ho fokotsa ts'ebetso ea nts'etsopele ea lithethefatsi.
Sehlahisoa sa rona se etsoa tlas'a mehato e thata ea ho laola boleng, ho netefatsa bohloeki bo phahameng le ho tsitsisa. Ka boemo ba bohloeki bo fetang 98%, 2-(5-aminopyrazin-2-yl) propan-2-ol e loketse mefuta e fapaneng ea likopo, ho kenyeletsoa k'hemistri ea meriana, ho sibolloa ha lithethefatsi, le lipatlisiso tsa thuto. Re utloisisa bohlokoa ba liphetho tse tšepahalang le tse ka hlahisoang hape mosebetsing oa hau, ke ka lebaka leo re behang boleng pele sehlopheng se seng le se seng.
Ntle le lisebelisoa tsa eona tse ikhethang tsa lik'hemik'hale, motsoako ona o boetse o tšehetsoa ke tšehetso e feletseng ea tekheniki le litokomane, e leng ho nolofalletsang bafuputsi ho e kenyelletsa mererong ea bona. Hore na o etsa meriana e mecha kapa o etsa lipatlisiso tse tsoetseng pele, 2-(5-aminopyrazin-2-yl) propan-2-ol ke khetho e nepahetseng bakeng sa litlhoko tsa hau.
Phahamisa boiteko ba hau ba lipatlisiso le nts'etsopele ka 2-(5-aminopyrazin-2-yl)propan-2-ol (CAS#1174231-20-9) – moo popontshwa e kopanang le botshepehi. Ikopanye le rona kajeno ho ithuta haholoanyane ka hore na komporo ena e ka ntlafatsa merero ea hau joang le ho tsamaisa katleho ea hau lefapheng la meriana.
