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1H-Pyrrolo[2 3-b]pyridine 6-methoxy-(CAS# 896722-53-5) Setšoantšo se Featured
  • 1H-Pyrrolo[2 3-b]pyridine 6-methoxy-(CAS# 896722-53-5) 1

1H-Pyrrolo[2 3-b]pyridine 6-methoxy-(CAS# 896722-53-5)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule C8H8N2O
'Misa oa Molar 148.16
Botenya 1.244±0.06 g/cm3(E boletsoeng esale pele)
Melting Point 88-89 °C
Boling Point 284.511°C ho 760 mmHg
Flash point 98.269°C
Khatello ea Mouoane 0.005mmHg ho 25°C
pKa 14.10±0.40(E boletsoeng esale pele)
Boemo ba polokelo E tiisitsoe ka ho omme, Mocheso oa Kamore
Refractive Index 1.647

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Matšoao a Kotsi Xn - E Kotsi
Likhoutu tsa Kotsi R22 – E kotsi ha e kwetswe
R36 – Ho teneha mahlong
Tlhaloso ea Tšireletseho 26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka.
WGK Jeremane 3
Sehlopha sa Likotsi TS'OALANG

 

Selelekela

6-methoxy-1H-cryrolo [2,3-b]pyridine ke motsoako oa organic o nang le foromo ea lik'hemik'hale C9H8N2O. Lintho tsa eona ke tse latelang:

 

1. Ponahalo: 6-methoxy-1H-chrrolo [2,3-b]pyridine ha e na 'mala ho kristale e mosehla.

2. sebaka se qhibilihang: hoo e ka bang 105-108 ℃.

3. Sebaka se belang: hoo e ka bang 325 ℃.

4. Sollubility: E qhibiliha ka har'a metsoako ea tlhaho e kang chloroform, methanol le dimethyl sulfoxide, 'me e qhibiliha hanyenyane metsing.

 

6-methoxy-1H-yrrolo [2,3-b]pyridine e na le litšebeliso tsa bohlokoa lipatlisisong tsa meriana le tsa lik'hemik'hale, tse kang:

 

1. Phekolo ea lithethefatsi: E sebelisoa haholo lipatlisisong le nts'etsopele ea li-anti-tumor, anti-inflammatory, anti-cancer le lithethefatsi tse ling.

2. Lik'hemik'hale tsa lik'hemik'hale: E le karolo ea bohlokoa ea lipakeng tsa tlhaho ea tlhaho, e ka sebelisoa ho haha ​​​​mehaho e rarahaneng ea limolek'hule.

 

Mekhoa ea ho lokisa 6-methoxy-1H-cryrolo [2,3-b]pyridine haholo-holo ke e latelang:

 

1. N-methylation reaction of indole: Indole e itšoara ka methyl halide ho hlahisa 6-methyl indole, ebe e itšoara ka N-methyl vinyl amine ho hlahisa 6-methoxy-1H-cryrolo [2,3-b] pyridine.

2. Redox reaction of indole: 6-methoxy-1H-pyridolo [2,3-b] pyridine e ka fumanoa ka ho itšoara ka indole ka sodium nitrite le tert-butyl peroxide.

 

Mabapi le tlhahisoleseding ea polokeho, ho na le lithuto tse fokolang tse mabapi le chefo le kotsi ea 6-methoxy-1H-pyridolo [2,3-b] pyridine, kahoo tlhahlobo e khethehileng ea tšireletso e hloka lipatlisiso tse eketsehileng. Ha ho etsoa liteko kapa lits'ebetso, ts'ebetso e nepahetseng ea liteko le mehato ea polokeho e lokela ho lateloa, ho qoba ho kopana ka kotloloho le letlalo le mahlo, ela hloko mehato ea ts'ireletso, 'me u qobe ho hema li-aerosol kapa lerōle. Haeba ho hlokahala, e lokela ho sebelisoa sebakeng se nang le moea o motle.

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